Evidence map›Paper›PMID 40728355›Full record

ArticleMicroscopy research and technique2025

Green Synthesis of Nickel Oxide Nanoparticles Using Leaf Extract of Aegle marmelos and Their Antibacterial, Anti-Oxidant, and In Vitro Cytotoxicity Activity.

Jawahar Sukumaran, Manogar Priya, Raja Venkatesan, Kiruthika Sathiasivan, Mohammad Rashid Khan, Seong-Cheol Kim

Abstract read
In one paragraph

Article in Microscopy research and technique, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Eco-Friendly Synthesis ofBioinorganic chemistry and applications · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jawahar SukumaranDepartment of Chemistry, School of Basic Sciences, VISTAS, Chennai, Tamil Nadu, India.
Manogar PriyaDepartment of Chemistry, School of Basic Sciences, VISTAS, Chennai, Tamil Nadu, India.
Raja VenkatesanDepartment of Biomaterials, Saveetha Dental College and Hospitals, SIMATS, Saveetha University, Chennai, Tamil Nadu, India.ORCID https://orcid.org/0000-0002-5547-7477
Kiruthika SathiasivanDepartment of Chemical Engineering, College of Engineering and Technology, SRM Institute of Science and Technology, Chennai, Tamil Nadu, India.
Mohammad Rashid KhanDepartment of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Seong-Cheol KimSchool of Chemical Engineering, Yeungnam University, Gyeongsan, Republic of Korea.

Funding

Ongoing Research Funding Program, King Saud University, Riyadh, Saudi Arabia ORF-2025-713
6 · The paper itself

Abstract

This present work employed a straightforward, green synthesis method to produce nickel oxide nanoparticles (NiO NPs) utilizing the leaf extract from the Aegle marmelos plant to improve their biological properties. NiO NPs have attracted considerable interest in recent years for their high chemical stability, catalytic performance, high surface area, biocompatibility, diverse applications, versatility, antimicrobial, anticancer, and antioxidant activity. The synthesized NPs underwent thorough characterization methods with UV-Visible spectroscopy (UV-Vis), Fourier transform infrared spectroscopy (FTIR), x-ray diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive x-ray spectroscopy (EDAX), and transmission electron microscopy (TEM) analysis indicated the NiO NPs were predominantly monoclinic, cubic, and hexagonal in shape, exhibiting high purity and a general crystalline size ranging from 10 to 25 nm. EDAX analysis confirmed the presence of nickel and oxygen elements. The in vitro cytotoxicity of the NiO NPs was investigated on MC3t3-E1 cell lines treated with six different concentrations (25, 50, 100, 150, 200, and 250 μg mL

Indexed as

AegleGreen Chemistry TechnologyMetal NanoparticlesNickelPlant ExtractsAnti-Bacterial AgentsAntioxidantsCell LineCytotoxicity Tests, ImmunologicCytotoxinsMicrobial Sensitivity TestsPlant LeavesAnti-Bacterial AgentsAntioxidantsCytotoxinsNickelnickel monoxidePlant ExtractsAegle marmelosantibacterialanti‐oxidantgreen synthesisin vitro cytotoxicity activityNiO NPs

Identifiers

PMID40728355
PMCPMC12414242

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.