ArticleJournal of the American Heart Association2025
Prevalence, Mechanisms, and Prognostic Impact of Effort Intolerance in Patients With Asymptomatic/Minimally Symptomatic Aortic Stenosis.
Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- The Prognostic Value of Exercise Stress Echocardiography in Asymptomatic Moderate and Severe Aortic Stenosis: A Systematic Review of Stress-Derived Hemodynamic and Functional Markers.Journal of clinical medicine · 2026Review
- Comprehensive Echocardiographic Assessment in Moderate Aortic Stenosis with Preserved Ejection Fraction Using Two-Dimensional Speckle-Tracking Echocardiography: Association with Functional Capacity.Journal of clinical medicine · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe aimed to investigate the prevalence and prognostic impact of effort intolerance in patients with asymptomatic/minimally symptomatic aortic stenosis and to study its determinants. METHODS AND
resultsOne hundred four patients with at least moderate asymptomatic/minimally symptomatic aortic stenosis (median age 79 years, 57% male) underwent 2-dimensional speckle tracking echocardiography and exercise-stress echocardiography with cardiopulmonary exercise test. Results indicated that 73% of patients have effort intolerance defined as %predicted peak V
conclusionsBoth aortic stenosis severity and extra-aortic cardiac injuries lead to effort intolerance. Strain Index and exercise indices such as tricuspid annular plane systolic excursion versus systolic pulmonary artery pressure and mean pulmonary artery pressure versus cardiac output slopes may be valuable for risk stratification in minimally symptomatic/asymptomatic aortic stenosis.
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