Evidence map›Paper›PMID 40728136›Full record

ArticleAngewandte Chemie (International ed. in English)2025

A Bambusuril Receptor Binds Charge Diffuse Anions in Water at Picomolar Concentrations.

Surbhi Grewal, Petr Slávik, Vladimír Šindelář

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Surbhi GrewalDepartment of Chemistry, Faculty of Science, Masaryk University, Kamenice 5, 625 00, Brno, Czech Republic.ORCID https://orcid.org/0000-0002-8314-5381
Petr SlávikDepartment of Chemistry, Faculty of Science, Masaryk University, Kamenice 5, 625 00, Brno, Czech Republic.
Vladimír ŠindelářDepartment of Chemistry, Faculty of Science, Masaryk University, Kamenice 5, 625 00, Brno, Czech Republic.ORCID https://orcid.org/0000-0003-0090-5961

Funding

Czech Infrastructure for Integrative Structural Biology CZ.02.01.01/00/23_015/0008175OP JAC - Project MSCAfellow7_MUNI CZ.02.01.01/00/22_010/0008854RECETOX Research Infrastructure LM2023069the Czech Science Foundation 23-05271Sthe European Union's Horizon 2020 Research and Innovation Programme 857560the National Infrastructure for Chemical Biology LM2023052
6 · The paper itself

Abstract

Anionic pollutants are widespread in the environment and pose risks to human health. Due to the typically low concentrations of these species, the development of efficient receptors for their detection and removal from aqueous solutions is highly desirable. Here, we report the design and synthesis of a bambusuril receptor with markedly enhanced anion-binding affinity in water, achieved by introducing trifluoromethyl electron-withdrawing groups. The resulting fluorinated receptor is, to date, the most potent known receptor for several charge diffuse anions in aqueous media. The most stable 1:1 host-guest complex in water was observed with iodide, exhibiting a relative dissociation constant of 59 pM. This complex is over three orders of magnitude more stable than any previously reported complex between an artificial receptor and inorganic anion in water.

Indexed as

BambusurilsBinding in waterChaotropic effectMacrocyclesSupramolecular chemistry

Identifiers

PMID40728136
PMCPMC12416460

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.