Evidence map›Paper›PMID 40728092›Full record

ArticleThe New phytologist2025

miR825-5p-regulated TNLs govern Arabidopsis resistance to Tetranychus urticae and Pieris brassicae.

Irene Rosa-Diaz, Diego Lopez-Marquez, Carmen R Beuzon, Isabel Diaz

Abstract read
In one paragraph

Article in The New phytologist, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Irene Rosa-DiazCentro de Biotecnología y Genómica de Plantas (CBGP), Universidad Politécnica de Madrid (UPM)-Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA/CSIC), Campus de Montegancedo, 20223, Madrid, Spain.ORCID https://orcid.org/0000-0002-3225-9995
Diego Lopez-MarquezDepartment of Biology, University of Copenhagen, Copenhagen N, DK-2200, Denmark.ORCID https://orcid.org/0000-0002-5923-4392
Carmen R BeuzonDepartamento de Biología Celular, Genética y Fisiología, Instituto de Hortofruticultura Subtropical y Mediterránea "La Mayora", Universidad de Málaga-Consejo Superior de Investigaciones Científicas (IHSM-UMA-CSIC), 29750, Málaga, Spain.ORCID https://orcid.org/0000-0002-6888-3845
Isabel DiazCentro de Biotecnología y Genómica de Plantas (CBGP), Universidad Politécnica de Madrid (UPM)-Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA/CSIC), Campus de Montegancedo, 20223, Madrid, Spain.ORCID https://orcid.org/0000-0001-9865-902X

Funding

ERDFER A way of making EuropeEuropean UnionIRD PRE2018-083375Ministerio de Ciencia Innovación y Universidades PDC32021-121055-100Ministerio de Ciencia Innovación y Universidades PID2020-115219RB-I00
6 · The paper itself

Abstract

MicroRNAs are essential regulators in plant resistance to biotic stresses, but their specific roles in the plant-herbivore context require deeper investigation. Here, we studied how the Arabidopsis miR825-5p differentially modulates certain TNLs (MRT1, MRT2, and MIST1), triggering defensive responses against the sucking acari Tetranychus urticae or the chewing insect Pieris brassicae. We demonstrated that the expression of miR825-5p is downregulated following T. urticae and P. brassicae infestation and identified miRNA TNL targets whose expression is induced by both feeders. miR825-5p downregulates MRT1 and MRT2, acting as a negative modulator of Arabidopsis basal resistance against T. urticae. A similar miR825-5p-mediated regulation of basal resistance, including MRT1 and MRT2 but also MIST1 silencing, is involved in the Arabidopsis response against P. brassicae. Moreover, miR825-5p triggered the production of MIST1-derived secondary interfering RNAs (phasiRNAs) and amplified silencing of MRT1 and MRT2. Taken together, our findings reveal the role of the miR825-5p/TNL module in controlling Arabidopsis response and adapting plant defenses based on the specific threat.

Indexed as

ArabidopsisArabidopsis ProteinsDisease ResistanceMicroRNAsPlant DiseasesTetranychidaeAnimalsGene Expression Regulation, PlantGene SilencingArabidopsis ProteinsMicroRNAsgene regulationmiR825‐5pnucleotide‐binding leucine‐rich repeat receptor proteinsPieris brassicaeplant defencesTetranychus urticae

Identifiers

PMID40728092
PMCPMC12371183

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.