SynthesisVeterinary medicine and science2025
Prevalence of Anti-Leptospira Antibodies in Bovines (2018-2023) and Reported Serovars and Serogroups-A Systematic Review With Meta-Analysis.
Synthesis in Veterinary medicine and science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- From Classical Bacterins to Recombinant Vaccines: Critical Aspects of the Immune Response in Ruminants.Microorganisms · 2026Review
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Authors and funding
4 authors.
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Abstract
introductionBovine leptospirosis is a globally distributed zoonotic disease that significantly impacts animal production and public health, leading to abortions and infertility in cattle. The aims of our study were (1) to quantitatively summarize the global and regional prevalence of anti-Leptospira antibodies in bovines and (2) to determine the most frequently reported serovars and serogroups affecting bovines.
methodsA systematic literature search was conducted across five electronic databases and a search engine. Eligible studies were published between January 2018 and December 2023 in English, Spanish, or Portuguese and used the MAT for diagnosis. The methodological quality of the documents was assessed using published guidelines. Multilevel random-effects logistic regression meta-analysis models for single proportions, with parameters calculated via maximum likelihood, were used to estimate the pooled prevalence of anti-Leptospira antibodies. Statistical heterogeneity was assessed using the Q and I
resultsThe meta-analysis included 77 studies, estimating global pooled seroprevalence of 39.5% (95% CI: 33.1%-46.3%). The pooled seroprevalence was 42.7% in the Americas (95% CI: 34.5%-51.4%), 44.3% in Europe (95% CI: 6.7%-89.8%), 37.5% in Asia (95% CI: 25.4%-51.4%), and 27.4% in Africa (95% CI: 19.9%-36.4%). In 55 studies, 18 serovars were identified, with a higher frequency observed in Hardjo (31.1%), Pomona (9.8%), and Icterohaemorrhagiae (8.2%). Additionally, 65 studies reported serogroup-specific seroprevalence, leading to Sejroe (54.9%), Pomona (9.9%), Icterohaemorrhagiae (8.5%), and Tarassovi (5.6%).
conclusionsThe high global seroprevalence of anti-Leptospira antibodies highlights the need for increased surveillance of leptospirosis in bovines. Preventive strategies should be improved to mitigate the effects of bovine leptospirosis in both animal production and public health.
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