Evidence map›Paper›PMID 40727985›Full record

ArticleJournal of primary care & community health

Is Rural Residence an Independent Risk Factor for Spontaneous Preterm Birth at a Midwestern Tertiary Care Center? A Cross-Sectional Study.

Abbie Lund, Barcey T Levy, Yinghui Xu, David A Bedell, Mark K Santillan

Abstract read
In one paragraph

Article in Journal of primary care & community health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Abbie LundThe University of Iowa Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, USA.ORCID 0009-0001-6613-164X
Barcey T LevyDepartment of Family and Community Medicine, The University of Iowa Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, USA.ORCID 0000-0002-3315-4116
Yinghui XuDepartment of Family and Community Medicine, The University of Iowa Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, USA.ORCID 0000-0002-5088-5092
David A BedellDepartment of Family and Community Medicine, The University of Iowa Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, USA.ORCID 0000-0001-6697-8026
Mark K SantillanDepartment of Obstetrics and Gynecology, The University of Iowa Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, USA.ORCID 0000-0002-3991-8017

Funding

The University of Iowa Clinical and Translational Science AwardUL1TR002537 · NCATS · UNIVERSITY OF IOWA · PI HANSEN, MARLAN R, WINOKUR, PATRICIA · 2018 to 2022
$20.0M
University of Iowa Institute for Clinical and Translational ScienceUM1TR004403 · NCATS · UNIVERSITY OF IOWA · PI Marlan R Hansen, Patricia Winokur · 2023 to 2026
$16.1M
University of Iowa Hawkeye Intellectual and Developmental Disabilities Research Center (Hawk-IDDRC)P50HD103556 · NICHD · UNIVERSITY OF IOWA · PI EDWIN TED G. ABEL, Lane Strathearn · 2021 to 2026
$8.5M
Vasopressin and Preeclampsia: Early Mechanisms for PreventionR01HD089940 · NICHD · UNIVERSITY OF IOWA · PI SANTILLAN, MARK K · 2019 to 2023
$1.9M
NCATS NIH HHS UL1 TR002537NCATS NIH HHS UM1 TR004403NICHD NIH HHS P50 HD103556NICHD NIH HHS R01 HD089940
6 · The paper itself

Abstract

objectiveAssess whether maternal rural residence was an independent risk factor (RF) for spontaneous preterm birth (sPTB) at a Midwest tertiary care center.

methodsAfter excluding deliveries complicated by indications for induced preterm birth, there were 16 974 deliveries among 13 339 women between May 1, 2009, and May 31, 2023. Standard descriptive statistics and Generalized Linear Mixed Models were used to identify RFs for sPTB.

resultsOf the 16 974 deliveries, 89.1% were full term, 28.8% were of rural mothers, and the mean maternal age was 29.6 years (y). 15.5% of rural deliveries were sPTBs versus only 9.1% of urban deliveries (P<.001). Significant independent RFs for sPTB included the extremes of maternal age (aOR, 2.14 for age 14 to <20 y and aOR, 3.37 for age ≥40 y) compared to age 20-<30 y, rural vs. urban residence (aOR, 1.56), maternal smoking (aOR, 2.47), transfer from an outside hospital (aOR, 671.3), and female sex of the baby (aOR, 0.79). With the transferred deliveries excluded these factors remained significant with similar aORs and Asian race was an additional significant protective factor (aOR, 0.57). Body mass index, race, ethnicity, type of medical insurance, and primigravidity were not significant RFs.

conclusionRural residence, extremes of maternal age, maternal smoking, female newborn sex, and transfer from an outside hospital were significant and independent RFs for sPTB.

Indexed as

Premature BirthRural PopulationAdolescentAdultCross-Sectional StudiesFemaleHumansInfant, NewbornMaternal AgeMidwestern United StatesPregnancyRisk FactorsTertiary Care CentersUrban PopulationYoung Adulthealth inequitieshealth outcomesobstetricspreterm birthrural healthunderserved communities

Identifiers

PMID40727985
PMCPMC12314244

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.