Evidence map›Paper›PMID 40727984›Full record

ArticleAnaesthesia2026

Age, ASA physical status and surgical outcomes: insights from a nationwide cohort study.

Naima Kilhamn, Jesper Eriksson, Erik von Oelreich, Malin Jonsson Fagerlund, Anders Oldner, Emma Larsson

Abstract read
In one paragraph

Article in Anaesthesia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Naima KilhamnDepartment of Perioperative Medicine and Intensive Care, Karolinska University Hospital, Stockholm, Sweden.ORCID 0000-0002-7797-9558
Jesper ErikssonDepartment of Perioperative Medicine and Intensive Care, Karolinska University Hospital, Stockholm, Sweden.
Erik von OelreichDepartment of Perioperative Medicine and Intensive Care, Karolinska University Hospital, Stockholm, Sweden.
Malin Jonsson FagerlundDepartment of Perioperative Medicine and Intensive Care, Karolinska University Hospital, Stockholm, Sweden.
Anders OldnerDepartment of Perioperative Medicine and Intensive Care, Karolinska University Hospital, Stockholm, Sweden.
Emma LarssonDepartment of Perioperative Medicine and Intensive Care, Karolinska University Hospital, Stockholm, Sweden.

Funding

Karolinska InstitutetStockholm läns landsting
6 · The paper itself

Abstract

introductionWith over 300 million surgical procedures performed worldwide annually and an ageing population with increasing comorbidities, peri-operative risk assessment is more important than ever. Whilst the ASA physical status is used widely to assess surgical risk, its association with age remains underexplored in contemporary, broad surgical populations. This study examines the relationship between ASA physical status, age and postoperative mortality in an adult surgical cohort.

methodsThis nationwide cohort study analysed data from the Swedish Perioperative Register on patients aged ≥ 18 y undergoing major non-cardiac surgery from January 2019 to March 2023. Data on comorbidities, socioeconomic factors and mortality were retrieved from national health registries. The primary outcome was 30-day mortality. Secondary outcomes were 365-day mortality and days at home alive at 30 days.

resultsA total of 262,938 elective and 197,108 acute procedures were analysed, with median ages of 66 and 68 y, respectively. Crude mortality rates in elective surgery were 1369 (0.5%) at 30 days and 10,437 (4.0%) at 365 days. For acute surgery, mortality was 10,602 (5.4%) at 30 days and 27,912 (14.2%) at 365 days. Adjusted odds ratios (OR) for 30-day mortality indicated a 14-fold increased risk for ASA physical status 3 compared with ASA physical status 1 in both elective (OR 13.7, 95%CI 7.5-25.0) and acute (OR 14.0, 95%CI 10.2-19.3) surgeries. Correspondingly, ASA physical status ≥ 4 was associated with odds ratios of 62.2 (95%CI 33.5-115.5) for elective and 51.1 (95%CI 37.1-70.3) for acute surgery. DISCUSSION: As populations age and surgical demand increases, continuous evaluation of risk assessment tools like the ASA physical status is essential. This study shows a strong association between ASA physical status and mortality across all ages in a contemporary adult surgical cohort. These findings could enhance our understanding of peri-operative risk stratification in the context of shifting demographic trends.

Indexed as

Postoperative ComplicationsSurgical Procedures, OperativeAdolescentAdultAgedAged, 80 and overAge FactorsCohort StudiesElective Surgical ProceduresFemaleHumansMaleMiddle AgedRegistriesRisk AssessmentSwedenepidemiologymajor surgerymortalitypostoperative

Identifiers

PMID40727984
PMCPMC12803587

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.