ArticleCase reports in infectious diseases2025
Acute Appendicitis Occurring in Dengue Fever: A Case Report and Review of the Literature.
Article in Case reports in infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of ultrasound to predict severe disease in patients with dengue and other viral infections associated with hemorrhagic fevers.PLoS neglected tropical diseases · 2026Pooled it
- Expanded Dengue and the Digestive System: A Systematic Review and Meta-Analysis.Tropical medicine and infectious disease · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dengue fever is a disease caused by the dengue virus and it is present in many tropical countries, including Nigeria. Cases of acute abdomen have been reported in dengue fever and they include acute cholecystitis, acute pancreatitis, acute appendicitis, and nonspecific peritonitis. This case report illustrates a case of acute appendicitis in dengue fever and aims to describe the relationship between both conditions. We report a case of a 25-year-old lady who presented with symptoms of dengue fever and was confirmed to have the disease. She was on treatment for dengue but subsequently developed acute appendicitis. She later underwent appendectomy and the appendix was confirmed to be inflamed both intraoperatively and histologically. Dengue virus can cause periappendiceal inflammation (periappendiceal fluid collection and mesenteric lymphadenopathy/adenitis) or acute appendicitis (which can progress to appendiceal perforation or appendicular mass formation). Periappendiceal inflammation presents with clinical features mimicking acute appendicitis but without appendicitis on ultrasonography or laparoscopy. Periappendiceal inflammation can also progress to appendicitis. For patients with dengue fever, diagnosis of acute appendicitis should not be based on clinical findings alone. Serial ultrasonography to confirm appendicitis is recommended. Conservative treatment with antibiotics should be the first line for acute appendicitis in dengue fever or periappendiceal inflammation in dengue. Surgical treatment is required in cases of appendiceal perforation or failure of conservative management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.