ArticleFrontiers in nutrition2025
Therapeutic efficacy of a galactoglucan from
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Structural Characterization, Constipation-Relieving, and Hypolipidemic Activity of Polysaccharides from Fresh and ProcessedFoods (Basel, Switzerland) · 2026Article
- Microbiota-immune crosstalk in the regulation of intestinal motility in constipation.Frontiers in microbiology · 2026Review
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Constipation is a prevalent gastrointestinal disorder demanding effective therapeutic strategies. This study investigated the therapeutic potential of Methods: PCP-g was purified from Results: PCP-g was identified as a homogeneous galactoglucan with a molecular weight of 7.49 × 10 Discussion: PCP-g effectively alleviates constipation by enhancing intestinal motility and fecal hydration. It modulates the PKA-AQP3 signaling pathway to improve colonic water permeability and positively influences the gut environment through the generation of SCFAs. These findings suggest that PCP-g may serve as a promising therapeutic candidate for the treatment of constipation, operating through aquaporin signaling and the regulation of the gut environment. The study advocates for further clinical trials and highlights the potential of edible mushroom polysaccharides in the management of constipation.
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Registered trials
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