Evidence map›Paper›PMID 40727628›Full record

ArticleBioMed research international2025

Efficacy of Topical Folic Acid in the Healing of Deep Second-Degree Burn Wound via Redox Modulation in Rat.

Ali Dalir, Shabnam Pourmoslemi, Sara Soleimani Asl, Pari Tamri

Abstract read
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Article in BioMed research international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ali DalirPharmaceutical Sciences Research Center, Institute of Cancer, Hamadan University of Medical Sciences, Hamadan, Iran.ORCID https://orcid.org/0000-0002-5663-178X
Shabnam PourmoslemiPharmaceutical Sciences Research Center, Institute of Cancer, Hamadan University of Medical Sciences, Hamadan, Iran.ORCID https://orcid.org/0000-0002-9014-4619
Sara Soleimani AslDepartment of Anatomical Sciences, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.ORCID https://orcid.org/0000-0003-1518-3308
Pari TamriPharmaceutical Sciences Research Center, Institute of Cancer, Hamadan University of Medical Sciences, Hamadan, Iran.ORCID https://orcid.org/0000-0001-9553-415X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Folic acid, synthetic form of folate, is necessary for synthesis and for repair of DNA. Studies have shown that folic acid enhances the DNA repair capacity of skin fibroblasts following tissue damage. The research objective was to assess the efficacy of topical folic acid on the treatment of second-degree burn wound in a rat model. The second-degree burn wounds were induced on the dorsal skin of Wistar rats. Animals were randomly placed into five groups (

Indexed as

BurnsFolic AcidWound HealingAdministration, TopicalAnimalsAntioxidantsDisease Models, AnimalHydroxyprolineMaleOxidation-ReductionOxidative StressRatsRats, WistarReactive Oxygen SpeciesSilver SulfadiazineSkinAntioxidantsFolic AcidHydroxyprolineReactive Oxygen SpeciesSilver Sulfadiazineantioxidantburn injuryfolic acidROSwound healing

Identifiers

PMID40727628
PMCPMC12301086

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.