Evidence map›Paper›PMID 40727624›Full record

ArticlePlastic and reconstructive surgery. Global open2025

Pilot Study: Blue Light Photobiomodulation for the Treatment of Complicated Wounds in Breast Surgery.

Massimo Ferrucci, Francesco Milardi, Daniele Passeri, Alessia De Col, Tajna Kraljic, Matteo Cagol, Tania Saibene, Silvia Michieletto, Alberto Marchet, Mariacristina Toffanin

Abstract read
In one paragraph

Article in Plastic and reconstructive surgery. Global open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Massimo FerrucciFrom the Breast Surgery Unit, Veneto Institute of Oncology IOV, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Padovaa, Italy.
Francesco MilardiGeneral Surgery, Department of Surgery, Oncology and Gastroenterology, University of Padovaa, Padovaa, Italy.
Daniele PasseriGeneral Surgery, Department of Surgery, Oncology and Gastroenterology, University of Padovaa, Padovaa, Italy.
Alessia De ColClinic of Plastic, Reconstructive and Aesthetic Surgery, Department of Neurosciences, University of Padova, Padova, Italy.
Tajna KraljicFrom the Breast Surgery Unit, Veneto Institute of Oncology IOV, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Padovaa, Italy.
Matteo CagolFrom the Breast Surgery Unit, Veneto Institute of Oncology IOV, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Padovaa, Italy.
Tania SaibeneFrom the Breast Surgery Unit, Veneto Institute of Oncology IOV, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Padovaa, Italy.
Silvia MichielettoFrom the Breast Surgery Unit, Veneto Institute of Oncology IOV, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Padovaa, Italy.
Alberto MarchetFrom the Breast Surgery Unit, Veneto Institute of Oncology IOV, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Padovaa, Italy.
Mariacristina ToffaninFrom the Breast Surgery Unit, Veneto Institute of Oncology IOV, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Padovaa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Blue light photobiomodulation has demonstrated efficacy in accelerating the healing process of chronic ulcers and various dermatologic conditions. Yet, its application in enhancing the healing of complicated postsurgical breast wounds, particularly in reconstructive surgery, remains unexplored. Methods: This pilot study included female patients who developed complicated wounds after reconstructive breast surgery at our institution between March 2022 and September 2023. All patients were treated with blue light therapy (EmoLED) in addition to standard wound care. We examined healing times, the number of EmoLED sessions required, and complication severity. Results: Among 27 female patients (median age 54 y), 74.1% underwent mastectomy with implant-based reconstruction, whereas the remaining patients underwent contralateral second-stage reduction mammaplasty. Over a 19-month median follow-up, 35 complications were recorded: 18 skin necroses, 9 partial nipple-areolar complex necroses, and 8 wound dehiscences. The median number of EmoLED sessions required was 5, typically administered weekly. A higher body mass index ( Conclusions: The use of blue light therapy accelerated and optimized the healing process in complicated postsurgical breast wounds. Larger prospective studies are warranted to further validate these findings.

Identifiers

PMID40727624
PMCPMC12303515

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.