ArticleClinical, cosmetic and investigational dermatology2025
Celiac Disease and Skin Diseases: A Bidirectional Mendelian Randomization Study.
Article in Clinical, cosmetic and investigational dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Mendelian randomization studies in atopic dermatitis: causal insights across omics layers.Frontiers in immunology · 2026Review
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Research as shown that celiac disease (CD) is associated with skin diseases, but their causality remains unclear. Therefore, this Mendelian randomization (MR) study evaluated the causality between CD and skin diseases. Methods: Bidirectional MR analysis was performed on single nucleotide polymorphism (SNP) candidates identified from genome-wide association study (GWAS) datasets using inverse variance weighted (IVW), weighted median, MR-egger, weighted mode and simple mode. Multivariate MR (MVMR) analysis was subsequently conducted by adjusting for BMI, smoking, and alcohol use. Result reliability was assessed by horizontal pleiotropy and heterogeneity testing. Results: IVW analysis revealed that CD increased the risk of atopic dermatitis (OR = 1.042, 95% CI: 1.018-1.067, Conclusion: CD contributes to higher risks of atopic dermatitis and cellulitis. Additionally, psoriasis is suggestively associated with CD. Nonetheless, further research is warranted to confirm these findings and to elucidate the underlying mechanisms.
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