Evidence map›Paper›PMID 40727570›Full record

ArticleOpen forum infectious diseases2025

The Impact of Point-of-Care Testing for Group A Streptococcal Pharyngitis on Antibiotic Prescribing and Patient Health Outcomes in Outpatient Care: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Ann-Sophie Mägdefrau, Carolin Kathner-Schaffert, Anni Matthes, Jutta Bleidorn, Robby Markwart

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ann-Sophie MägdefrauJena University Hospital, Institute of General Practice and Family Medicine, Friedrich Schiller University Jena, Jena, Germany.
Carolin Kathner-SchaffertJena University Hospital, Institute of General Practice and Family Medicine, Friedrich Schiller University Jena, Jena, Germany.
Anni MatthesJena University Hospital, Institute of General Practice and Family Medicine, Friedrich Schiller University Jena, Jena, Germany.ORCID https://orcid.org/0000-0003-1765-0344
Jutta BleidornJena University Hospital, Institute of General Practice and Family Medicine, Friedrich Schiller University Jena, Jena, Germany.
Robby MarkwartJena University Hospital, Institute of General Practice and Family Medicine, Friedrich Schiller University Jena, Jena, Germany.ORCID https://orcid.org/0000-0003-0338-3433

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Point-of-care testing (POCT) for group A β-hemolytic Methods: Medline, Web of Science, Scopus, and Cochrane Central Register of Controlled Trials were searched for randomized controlled trials (RCTs; January 2000-January 2025). Random-effects models were used to calculate pooled risk ratios (RRs) with 95% confidence intervals (CIs) for summary effect sizes. Results: From 15 097 unique records, we identified 8 eligible RCTs comparing the use of StrepA POCTs with standard care. The use of StrepA POCTs reduced the number of antibiotics prescribed by 38% (RR, 0.62 [95% CI, .51-.77]; Conclusions: The use of StrepA POCTs in children and adults with signs of pharyngitis likely reduces the number of antibiotics prescribed without compromising patient health outcomes.

Indexed as

antibiotic prescribinggroup A β-hemolytic Streptococcuspharyngitispoint-of-care testsrapid diagnostic tests

Identifiers

PMID40727570
PMCPMC12301963

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.