Evidence map›Paper›PMID 40727544›Full record

ArticleUrology case reports2025

Cough-associated detrusor overactivity resolved after intravesical onabotulinumtoxin A injection: A case report.

Rie Yoshimura, Nobutaka Shimizu, Mio Togo, Shinkuro Yamamoto, Tomoya Nao, Tsutomu Shimamoto, Hideo Fukuhara, Satoshi Fukata, Shingo Ashida, Takashi Karashima and 2 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Urology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rie YoshimuraDepartment of Urology, Kochi Medical School, Kochi University, Nankoku, Japan.
Nobutaka ShimizuPelvic Floor Center, Kochi Medical School, Kochi University, Nankoku, Japan.
Mio TogoPelvic Floor Center, Kochi Medical School, Kochi University, Nankoku, Japan.
Shinkuro YamamotoDepartment of Urology, Kochi Medical School, Kochi University, Nankoku, Japan.
Tomoya NaoDepartment of Urology, Kochi Medical School, Kochi University, Nankoku, Japan.
Tsutomu ShimamotoDepartment of Urology, Kochi Medical School, Kochi University, Nankoku, Japan.
Hideo FukuharaDepartment of Urology, Kochi Medical School, Kochi University, Nankoku, Japan.
Satoshi FukataDepartment of Urology, Kochi Medical School, Kochi University, Nankoku, Japan.
Shingo AshidaDepartment of Urology, Kochi Medical School, Kochi University, Nankoku, Japan.
Takashi KarashimaDepartment of Urology, Kochi Medical School, Kochi University, Nankoku, Japan.
Motoaki SaitoDepartment of Pharmacology, Kochi Medical School, Kochi University, Nankoku, Japan.
Keiji InoueDepartment of Urology, Kochi Medical School, Kochi University, Nankoku, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 68-year-old woman developed urgency urinary incontinence (UUI) one month after tension-free vaginal tape (TVT) surgery for stress urinary incontinence. Pharmacological treatment was ineffective. Pressure-flow study revealed cough-associated detrusor overactivity (CADO). An intravesical injection of 100 U botulinum toxin resolved symptoms and normalized bladder sensation. Six months later, CADO recurred and was successfully treated with a second injection. No adverse events occurred. CADO is often misdiagnosed as stress incontinence, and accurate diagnosis requires urodynamic evaluation. This case highlights the potential of intravesical botulinum toxin for managing CADO, including recurrence. Further studies should establish optimal diagnostic strategies and long-term efficacy.

Indexed as

Cough-associated detrusor overactivityIntravesical botulinum toxin injectionReoperationStress urinary incontinence

Identifiers

PMID40727544
PMCPMC12301800

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.