ArticleJournal of global infectious diseases
A Systematic Review and Meta-analysis of Scrub Typhus and its Association with Liver Disease.
Article in Journal of global infectious diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Korat-Scrub Typhus Score: A Clinical Tool for Predicting Scrub Typhus in Patients With Acute Undifferentiated Febrile Illness.Tropical medicine & international health : TM & IH · 2026Article
- The State of the Globe - Overview of Liver Involvement in Scrub Typhus.Journal of global infectious diseasesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Scrub typhus is a vector-borne infection caused by the bacterium Methods: Data sources PubMed, Cochrane, and Google Scholar were systematically searched for data published up to May 2024. The studies selected were all scrub typhus patients associated with liver diseases. The data extraction was done as per the preestablished checklist. The mean difference for liver function test (LFT)'s aspartate aminotransferease and alanine aminotransferase level was analyzed, and risk difference was evaluated with liver disease and mortality rate using RevMan 5.4 software. Data analyses were performed from 2019 to 2024 (PROSPERO Registration: ID CRD42024515922). Results: The analysis included a total of 901 scrub typhus cases with 554 cases associated with liver diseases. The study further investigated the LFT parameters, clinical symptoms, and 129 case mortality of scrub typhus. The meta-analyses showed that AST and ALT levels of scrub typhus patients had an overall significant effect in scrub typhus with liver disease (95% confidence interval [CI]: 135.81-153.15) with Conclusion: 61.50% scrub typhus with liver disease patients and 14.32% mortality rate in scrub typhus were evaluated. This study demonstrated an association betweeen scrub typhus and liver disease, highlighting its severity and the mortality rate among hospitalized patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.