Evidence map›Paper›PMID 40727497›Full record

ArticleJournal of global infectious diseases

Encapsulation of a Novel

Sonia Bhonchal Bhardwaj, Sanjay Chhibber, Shaveta Sood, Manjula Mehta, Jyoti Sharma

Abstract read
In one paragraph

Article in Journal of global infectious diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sonia Bhonchal BhardwajDepartment of Microbiology, Dr. Harvansh Singh Judge Institute of Dental Sciences and Hospital, Panjab University, Chandigarh, India.
Sanjay ChhibberDepartment of Microbiology, Panjab University, Chandigarh, India.
Shaveta SoodDepartment of Periodontics, Panjab University, Chandigarh, India.
Manjula MehtaDepartment of Microbiology, Dr. Harvansh Singh Judge Institute of Dental Sciences and Hospital, Panjab University, Chandigarh, India.
Jyoti SharmaDepartment of Microbiology, Dr. Harvansh Singh Judge Institute of Dental Sciences and Hospital, Panjab University, Chandigarh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Methods: In this study, a novel Results: The phage isolated was lytic belonging to Siphoviridae family. The mean diameter of the chitosan-alginate microspheres was 1.7 ± 0.13 mm. The pore size of the phage-loaded chitosan-alginate shell was less than 100 nm, resulting in sustained release of the phages. The chitosan-alginate encapsulated phage was stable for a long time (6 h) in simulated saliva. The encapsulated phage could withstand exposure to different pH (pH 2, pH 4, and pH 7) in simulated saliva. It was also stable at different temperatures (4°C, 37°C, and 60°C). Conclusion: The encapsulated phage has the potential to be used as phage therapy in oral diseases. Further, the chitosan-alginate encapsulated phage microsphere can be incorporated in a patch/membrane/gel in combination with antibiotics/nutritional components/anti-inflammatory agents as treatment for oral diseases induced by

Indexed as

BacteriophageEnterococcus faecalisoral diseasesphage encapsulationphage therapy

Identifiers

PMID40727497
PMCPMC12294147

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.