Trial reportRisk management and healthcare policy2025
High-Flow Nasal Oxygen Prolongs Safe Apnea Time in Obstructive Sleep Apnea Patients Undergoing General Anesthesia: A Randomized Controlled Trial.
Trial report in Risk management and healthcare policy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- High-Flow Nasal Cannula Oxygen Therapy in Perioperative Respiratory Care: Application and Prospects.Journal of multidisciplinary healthcare · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Patients with obstructive sleep apnea (OSA) are at high risk for rapid oxygen desaturation during anesthesia induction. Apneic oxygenation with high-flow nasal oxygen (HFNO) has proven effective in prolonging safe apnea time in various patient populations. However, evidence for the efficacy of HFNO in OSA patients remains limited. This study aimed to evaluate whether the use of HFNO during anesthesia induction in OSA patients prolongs safe apnea time. Methods: In this prospective randomized clinical trial, all participants underwent standardized pre-oxygenation and anesthesia induction. During the apneic period, oxygen was delivered either via HFNO at 60L/min (HFNO group) or with the nasal cannula left in place but disconnected from the oxygen source (control group, no supplemental oxygen). The primary outcome of this study was the time to peripheral oxygen desaturation (SpO Results: The HFNO group demonstrated a significantly prolonged safe apnea time compared to the Control group (18.1 [12.1,18.8] vs 4.2 [2.5,6.3] minutes; Conclusion: In this randomized controlled trial, HFNO significantly prolongs safe apnea time and enhances oxygenation during anesthesia induction in OSA patients. These findings highlight the potential of HFNO to improve perioperative airway management and patient safety in this high-risk population.
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Registered trials
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