Evidence map›Paper›PMID 40727480›Full record

ArticleJCEM case reports2025

Cutaneous Limited Langerhans Cell Histiocytosis Complicated by Late-onset Panhypopituitarism.

Nehaal Ahmed, Caroline Davidge-Pitts, Emma Johnson, Jason Young, Ronald S Go

Abstract readCase Reports
In one paragraph

Article in JCEM case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nehaal AhmedDivision of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA.ORCID https://orcid.org/0009-0006-5314-9281
Caroline Davidge-PittsDivision of Endocrinology, Diabetes, Nutrition, Mayo Clinic, Rochester, MN 55905, USA.ORCID https://orcid.org/0000-0002-9393-7745
Emma JohnsonDepartment of Dermatopathology, Mayo Clinic, Rochester, MN 55905, USA.
Jason YoungDepartment of Radiology, Mayo Clinic, Jacksonville, FL 32202, USA.
Ronald S GoDepartment of Hematology, Mayo Clinic, Rochester, MN 55905, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder infrequently complicated by delayed-onset pituitary disease. A 41-year-old female presented with papular, acneiform skin lesions. Shave biopsy demonstrated a superficial dermal epithelioid cell proliferation with S100, CD1a, and langerin positivity on immunohistochemistry and a

Indexed as

arginine vasopressin deficiencyLangerhans cell histiocytosispanhypopituitarism

Identifiers

PMID40727480
PMCPMC12301716

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.