ReviewJournal of inflammation research2025
Mechanisms and Clinical Application Prospects of Curcumin in the Treatment of Sepsis.
Review in Journal of inflammation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Effects of Curcumin on Vascular Endothelial Function, Lipid Metabolism, Inflammation and Neuroprotection-A Review.Nutrients · 2026Pooled it
- The efficacy of artesunate in animal models of sepsis: a systematic review and meta-analysis.Frontiers in pharmacology · 2026Pooled it
- Development of a Novel Curcumin-Vanillic Acid Eutectic: Physicochemical Characterization, Antioxidant Activity, and Bioavailability Enhancement.Pharmaceutical research · 2026Article
- Identification and validation of potential shared diagnostic markers for sepsis-induced ARDS and cardiomyopathy via WGCNA and machine learning.Frontiers in molecular biosciences · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sepsis is a systemic inflammatory response syndrome caused by pathogenic microorganisms such as bacteria, fungi, viruses, and parasites invading the body. It is primarily characterized by an immune dysregulation in response to infection, leading to severe complications such as dysfunction of vital organs, shock, and disseminated intravascular coagulation (DIC), thereby threatening the patient's life. Additionally, approximately 3 million surviving patients suffer from cognitive impairment, severely affecting their quality of life. Curcumin, a monomer of traditional Chinese medicine, has extensive pharmacological activity. Numerous studies have shown that curcumin can counteract the inflammatory response in sepsis and protect against organ damage caused by sepsis, suggesting that curcumin may become a new direction for sepsis treatment. In this review, we summarize the therapeutic effects and detailed mechanisms of curcumin in the treatment of sepsis based on current research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.