ArticleInfection and drug resistance2025
Management of Invasive Bronchopulmonary Mucormycosis with Low-Dose Antifungal Therapy and Left Lower Lobectomy in a Patient with Renal Insufficiency.
Article in Infection and drug resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: This case report aims to evaluate the feasibility of medical and surgical management in a patient with invasive bronchopulmonary mucormycosis complicated by renal insufficiency-a critical challenge limiting antifungal dosing and requiring tailored therapeutic strategies, while also reviewing the current literature on the treatment of pulmonary mucormycosis. Case Presentation: The patient received low-dose antifungal therapy with posaconazole and amphotericin B cholesterol sulfate complex. Subsequently, the patient underwent a left inferior lobectomy and experienced a successful postoperative recovery. Renal insufficiency complicates drug selection and dosing. A literature review demonstrated that combining antifungal therapy with surgical intervention is an effective approach for treating invasive bronchopulmonary mucormycosis. Conclusion: The combination of antifungal therapy and surgical management proves to be an effective treatment strategy for invasive bronchopulmonary mucormycosis in patients with renal insufficiency.
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