Evidence map›Paper›PMID 40727354›Full record

ArticleQuantitative imaging in medicine and surgery2025

Efficacy and safety of ultrasound-guided percutaneous aspiration-sclerotherapy with anhydrous ethanol for adult simple renal cyst: a multicenter, prospective, randomized controlled trial.

Shu Luo, Ping Feng, Yongzhong Li, Shuhua Shi, Lichuan Yang, Yanrong Yang, Rongchen Wang, Xuelian Chen, Jiaojiao Zhou

Abstract read
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Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Shu Luo *Department of Ultrasound, West China Hospital, Sichuan University, Chengdu, China.
Ping Feng *Clinical Trial Center and National Medical Products Administration Key Laboratory for Clinical Research and Evaluation of Innovative Drugs, West China Hospital, Sichuan University, Chengdu, China.
Yongzhong LiDepartment of Ultrasound, West China Hospital, Sichuan University, Chengdu, China.
Shuhua ShiDepartment of Ultrasound, West China Hospital, Sichuan University, Chengdu, China.
Lichuan YangDepartment of Nephrology, West China Hospital, Sichuan University, Chengdu, China.
Yanrong YangDepartment of Ultrasound, West China Women's and Children's Hospital, Sichuan University, Chengdu, China.
Rongchen WangDepartment of Ultrasound, West China Hospital, Sichuan University, Chengdu, China.
Xuelian ChenDepartment of Ultrasound, West China Hospital, Sichuan University, Chengdu, China.
Jiaojiao ZhouDepartment of Ultrasound, West China Hospital, Sichuan University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Percutaneous aspiration-sclerotherapy (PAS) is one of the most common treatments for renal cysts. In this study, we conducted an unequal-group, superior, randomized controlled trial to evaluate the safety and efficacy of ultrasound-guided PAS with anhydrous ethanol involving single-session multiple injections for simple renal cysts (SRCs) in adults by comparing percutaneous aspiration therapy with or without sclerosis agents. Methods: We prospectively collected data from multiple healthcare organizations in China on 149 patients with SRCs from August 2017 to October 2018. The patients enrolled in the study underwent percutaneous aspiration therapy with (treatment group, n=120) or without (control group, n=29) anhydrous ethanol. Treatment success was defined as a reduction in renal cyst volume of 87.5% or more from pre-treatment volume after 24 weeks of treatment. All patients were followed up at weeks 12 and 24. The patient profiles, reduced volume of cysts, treatment success rates, recurrence rates, and complication rates of two groups were compared. Results: In this trial, the analysis of Full Analysis Set (FAS) revealed an average volume reduction of 93.4 mL in the treatment group (PAS with anhydrous ethanol) and 69.8 mL in the control group (percutaneous aspiration treatment) (P<0.01). At the 24-week follow-up, the treatment success rate of the treatment group was significantly higher than that of the control group (90.43% Conclusions: PAS with anhydrous ethanol combined with single-session multiple injections is a safe and effective treatment for SRCs. Trial Registration: Chinese Clinical Trial Registry identifier: ChiCTR-TRC-10001114.

Indexed as

anhydrous ethanolsclerotherapySimple renal cysts (SRCs)ultrasound

Identifiers

PMID40727354
PMCPMC12290762

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.