ArticleOphthalmology science
Elevated Intraocular Pressure Immediately after Cataract Surgery and Future Risk of Primary Open-Angle Glaucoma in the IRIS® Registry (Intelligent Research in Sight).
Article in Ophthalmology science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Long-Term Intraocular Pressure Changes Following Phacoemulsification in Eyes with and Without Primary Open-Angle Glaucoma.Medicina (Kaunas, Lithuania) · 2026Article
- Comparison of Two Techniques in Phacoemulsification: Hydroimplantation and Viscoimplantation.Beyoglu eye journal · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study evaluated associations between postoperative intraocular pressure (IOP) after cataract surgery and the future risk of developing primary open-angle glaucoma (POAG) in patients without prior glaucoma, glaucoma suspect, or ocular hypertension diagnoses. Design: Retrospective cohort study. Subjects: 1 912 101 individuals without prior glaucoma, glaucoma suspect, or ocular hypertension diagnoses who underwent their first cataract surgery in the American Academy of Ophthalmology IRIS® Registry (Intelligent Research in Sight). Methods: The highest IOP recorded on postoperative days 0 to 2 was used for analysis. For Kaplan-Meier survival estimates and Cox proportional hazards model analysis, IOP was dichotomized into normal (≤21 mmHg) and high (>21 mmHg) and assessed for associations with POAG. The stratified Cox model quantified the associations between IOP and the risk of POAG across different demographic groups. Additionally, postoperative IOP was divided into decile categories, and hazard ratios (HRs) of the risk of POAG were estimated for each, with the 40% to 60% IOP range as the reference, adjusting for demographic factors. Main Outcome Measures: Cumulative probability of POAG diagnosis and HRs for POAG development. Results: The median time to development of POAG was 682 days (interquartile range 191-1467 days). Kaplan-Meier estimates showed that the 4000-day cumulative probability of POAG diagnosis for the high IOP group was nearly double the normal group (3.4% vs. 1.7%, Conclusions: Elevated postoperative IOP after cataract surgery is a risk factor for future POAG development, independent of age, sex, race, and ethnicity. Financial Disclosures: Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.
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Registered trials
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