Evidence map›Paper›PMID 40727285›Full record

ReviewRSC advances2025

Precision nanomaterials in colorectal cancer: advancing photodynamic and photothermal therapy.

Yuhan Chen, Dong Tang

Abstract readReview
In one paragraph

Review in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yuhan ChenClinical Medical College, Yangzhou University Yangzhou 225000 People's Republic of China 2704766140@qq.com.ORCID https://orcid.org/0009-0006-6965-4549
Dong TangDepartment of General Surgery, Institute of General Surgery, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, The Yangzhou Clinical Medical College of Xuzhou Medical University, The Yangzhou School of Clinical Medicine of Dalian Medical University, The Yangzhou School of Clinical Medicine of Nanjing Medical University, Northern Jiangsu People's Hospital, Clinical Teaching Hospital of Medical School, Nanjing University Yangzhou 225000 China 83392785@qq.com.ORCID https://orcid.org/0009-0009-6687-3617

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanomaterials, due to their unique size, excellent targeting ability, and good biocompatibility, have gradually gained attention in oncologic medical treatments. Photodynamic therapy (PDT) and photothermal therapy (PTT), known for their low side effects and minimal trauma, are widely used in immunotherapy for malignant tumors. However, limitations such as low light penetration depth, poor targeting, and localized thermal effects restrict the application scope of photothermal dynamic therapy. Clinical studies have found that nano-mediated targeted drug carriers exhibit low toxicity and good biocompatibility. Furthermore, the superior photothermal conversion performance of nanomaterials can significantly enhance the efficacy of photothermal dynamic therapy in colorectal cancer treatment. Nanomaterials, which have been involved in various cancer treatment processes, represent an emerging medical biomaterial. This review systematically explores the types of nanomaterials currently commonly applied in medicine, with a particular focus on their breakthroughs and cutting-edge research in photodynamic therapy (PDT) and photothermal therapy (PTT) for colorectal cancer. It also discusses the future prospects and improvement strategies of nanomaterials in precision medicine.

Identifiers

PMID40727285
PMCPMC12291162

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.