Evidence map›Paper›PMID 40727152›Full record

ArticleIndian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India2025

Castleman's Disease-Unicentric Neck Lymphadenoapthy: Case Report and Review of Literature.

Arsheed Hussain Hakeem, Novfa Iftikhar, Michelle D Padua

Abstract read
In one paragraph

Article in Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Arsheed Hussain HakeemApollo Cancer Institute, Hyderabad, 500096 India.ORCID 0000-0002-6714-7264
Novfa IftikharDepartment of Internal Medicine, Government Medical College Srinagar, Srinagar, India.
Michelle D PaduaApollo Cancer Institute, Hyderabad, 500096 India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Castleman's disease is rare lymphoproliferative disorder mostly seen in the mediastinum. We report a case of Castleman's disease involving a single lymph node at the left level II A in a 27-year-old female whose definitive diagnosis was made only on histological examination. Isolated Castleman's disease of the level II A lymph node is rare and a thorough clinical and histological examination is necessary to rule out the systemic form of the disease. Clinically two types of the Castleman's disease are seen, a unicentric variety where either a single lymph node or region is involved microscopically and multicentric variety where various lymph node regions are involved. Surgical excision is the standard of management for the unicentric Castleman's disease and has good prognosis, whereas the multicentric type is associated with systemic symptoms and has a poor prognosis. Although, microscopically, they can be classified as-hyaline vascular, plasma cell, transitional and stromal rich type, but their clinical significance is not clear.

Indexed as

AutoimmuneCastleman’s diseaseLymphadenopathy

Identifiers

PMID40727152
PMCPMC12297124

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.