ArticleIndian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India2025
Effect of Proton Pump Inhibitor on Quality of Life of Patients with Laryngopharyngeal Reflux.
Article in Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Laryngopharyngeal reflux (LPR) is a common disease in the outpatient department of otolaryngology and is characterised by backflow of stomach contents into the pharynx and larynx resulting in significant negative impact on the quality of life of patients. The aim of study was to assess the effect of proton pump inhibitor (PPI) on quality of life in patients with LPR. Method: 110 patients diagnosed with LPR were enrolled in study and prescribed omeprazole (20 mg) twice daily for 12 weeks. The Reflux Symptom Index (RSI), Reflux Finding Score (RFS) and LPR-health-related quality of life (HRQOL) were recorded for each patient at the initial visit and at 4th, 8th and 12th week follow-up visits. Results: Mean RSI, RFS, HRQOL was 15.28 ± 1.19, 12.65 ± 1.16 and 77.77 ± 11.80 respectively at baseline. Significant improvement was observed in RSI and RFS scores after treatment. The HRQOL score also showed gradual improvement after PPI treatment. Conclusion: PPI treatment brought about a significant improvement in signs, symptoms and quality of life of LPR patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.