ArticleFrontiers in pharmacology2025
Exploring the therapeutic mechanism of itraconazole combined with ritonavir on
Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- Integration of FAERS database and network toxicology to investigate adverse drug events and potential toxicological mechanisms of triazole antifungal agents.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Integrated Multi-Omics Analysis of a Periplaneta americana Symbiont Streptomyces sampsonii Strain WA1-19 Against Candida albicans.Microbial biotechnology · 2026Article
- Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Autophagy induced by itraconazole and ritonavir was found involved in the pathogenesis of Methods: The overlapping targets of itraconazole and ritonavir, and those-related to Results: PPI network showed that PIK3R1, RELA, STAT3, HSP90AA1, TP53, JUN, GRB2, EGFR, ESR1 and TNF were potential core targets of autophagy therapy for Conclusion: Network pharmacological analysis showed a multi-target and multi-pathway molecular mechanism of itraconazole and ritonavir in the treatment of
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Registered trials
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