Evidence map›Paper›PMID 40727085›Full record

ArticleParasite epidemiology and control2025

Diagnostic performance evaluation of ParaEgg for identifying intestinal helminthiasis: A comparative study with conventional copromicroscopy.

Tilak Chandra Nath, Heeil Lee, Md Mahamudul Hasan, Tanmoy Roy Rudro, Dipta Das, Md Taufiqur Rahman, Nandiny Saha Roy, Pritha Parial, Proloy Chakraborty Tusher, Tarek Siddiki

Abstract read
In one paragraph

Article in Parasite epidemiology and control, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tilak Chandra NathDepartment of Parasitology, Sylhet Agricultural University, Bangladesh.
Heeil LeeKDCA-SAU Youth Club, Sylhet Agricultural University, Bangladesh.
Md Mahamudul HasanFaculty of Veterinary, Animal and Biomedical Sciences, Sylhet Agricultural University, Bangladesh.
Tanmoy Roy RudroFaculty of Veterinary, Animal and Biomedical Sciences, Sylhet Agricultural University, Bangladesh.
Dipta DasFaculty of Veterinary, Animal and Biomedical Sciences, Sylhet Agricultural University, Bangladesh.
Md Taufiqur RahmanFaculty of Veterinary, Animal and Biomedical Sciences, Sylhet Agricultural University, Bangladesh.
Nandiny Saha RoyFaculty of Veterinary, Animal and Biomedical Sciences, Sylhet Agricultural University, Bangladesh.
Pritha ParialFaculty of Veterinary, Animal and Biomedical Sciences, Sylhet Agricultural University, Bangladesh.
Proloy Chakraborty TusherDepartment of Parasitology, Sylhet Agricultural University, Bangladesh.
Tarek SiddikiDepartment of Parasitology, Sylhet Agricultural University, Bangladesh.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Intestinal helminthiasis remains a significant public health concern in Bangladesh, affecting both humans and animals. Conventional copromicroscopic methods, though widely used, often lack sensitivity, particularly in areas with low prevalence and intensity of infection. ParaEgg, a new diagnostic tool, has been developed to improve the efficiency of copromicroscopic detection. This study aimed to evaluate the diagnostic performance of ParaEgg in detecting intestinal helminth infections in humans and dogs compared to commonly used traditional methods. Methods: A cross-sectional study was conducted from August to November 2024, analyzing 100 human stool samples and 100 dog fecal samples. For human samples, ParaEgg was compared with Formalin-Ether Concentration Technique (FET), Sodium Nitrate Flotation (SNF), Harada Mori Technique (HM), and Kato-Katz Smear (KK). For animal samples, ParaEgg was evaluated against FET, SNF, and HM. Diagnostic performance was assessed using sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV), with the composite results of all methods serving as the gold standard. Additionally, ParaEgg's efficacy was evaluated using naturally infected and experimentally seeded ( Results: The overall helminth infection rates were 24 % in humans and 53 % in dogs. In humans, five types of helminth genera ( Conclusion: These findings highlight ParaEgg as an effective diagnostic tool, comparable to Kato-Katz Smear and superior to traditional methods. Its ability to detect mixed infections, egg recovery rate and its high sensitivity in both human and animal samples underscore its potential for widespread application in field settings.

Indexed as

CopromicroscopyDiagnostic toolIntestinal helminthiasisParaEggSensitivity and specificity

Identifiers

PMID40727085
PMCPMC12303041

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.