ArticleWorld journal of clinical cases2025
Tired of the confusion around pleural effusions: Adenosine deaminase detection sets the record straight!
Article in World journal of clinical cases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Pleural effusion, characterized by the accumulation of fluid in the pleural space, poses significant challenges in clinical practice, especially in determining whether it belongs to the inflammatory exudates or non-inflammatory transudates. Adenosine deaminase (ADA), an enzyme primarily produced by immune cells, particularly lymphocytes, increase in response to inflammatory conditions, including tuberculosis and malignancies. Elevated ADA levels in pleural have been shown to correlate with inflammatory exudates, making it a valuable biomarker for differentiating between inflammatory and non-inflammatory effusions. Moreover, numerous studies have demonstrated the treatment function of ADA in inflammation- related pleural effusion syndrome. Recently, research has established the values for the implication of ADA in diagnosing and managing pleural disease. Based on these findings, ADA becomes a reliable, non-invasive marker for early diagnosis and the appropriate treatment for pleural inflammation, ultimately improving patient outcomes.
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