Evidence map›Paper›PMID 40726877›Full record

ArticleCureus2025

Adult-Onset Multisystem Langerhans Cell Histiocytosis With Bone and Hepatic Involvement: A Rare Case With Radiologic-Pathologic Correlation.

Yanni Zulia, Christopher D Louviere, Abdullah Mohamed, Anwer Siddiqi, Renato Abu Hana

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yanni ZuliaRadiology, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
Christopher D LouviereRadiology, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
Abdullah MohamedPathology and Laboratory Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
Anwer SiddiqiPathology, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
Renato Abu HanaRadiology, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Langerhans cell histiocytosis (LCH) is a rare proliferative disorder of histiocytic dendritic cells that can mimic metastatic malignancies due to its potential for multiorgan involvement. Histopathologic confirmation is essential for accurate diagnosis. As such, biopsy is imperative, especially in patients who present with hepatic lesions. Adjunctive liver imaging can help confirm the diagnosis, but is rarely performed. Little information is available on imaging features of hepatic involvement in LCH. Here we report a case of a 22-year-old man with a fracture of his cervical spine suspicious for pathological fracture. However, liver imaging and confirmatory histopathology revealed LCH instead of metastatic spread.

Indexed as

ct angiogramimmunostaininglangerhans cell histiocytosis(lch)metastasisreticuloendothelial system

Identifiers

PMID40726877
PMCPMC12303229

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.