Evidence map›Paper›PMID 40726875›Full record

ArticleCureus2025

Impact of Neighborhood Disadvantage on Gastrointestinal Morbidity in Extremely Low Birthweight Infants.

Samantha Shaffer, Katie A Huff, James Slaven, Seethal A Jacob, Jason Z Niehaus

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Samantha ShafferPediatrics, Indiana University School of Medicine, Indianapolis, USA.
Katie A HuffNeonatology, Indiana University School of Medicine, Indianapolis, USA.
James SlavenBiostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, USA.
Seethal A JacobPediatric Hematology/Oncology, Riley Hospital for Children, Indianapolis, USA.
Jason Z NiehausNeonatology, Indiana University School of Medicine, Indianapolis, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNecrotizing enterocolitis (NEC) and spontaneous intestinal perforation (SIP) are major causes of morbidity and mortality in extremely low birth weight (ELBW) infants. Social determinants of health (SDH) are associated with disparate outcomes for neonates admitted to the neonatal intensive care unit (NICU). This study sought to identify correlations between NEC, SIP, and SDH.

methodsRetrospective cohort study of infants born between 22 and 25 weeks of gestation between 2017 and 2023. Utilizing the area deprivation index (ADI) as a marker for social vulnerability.  Results: The study included 156 patients. Infants with NEC had a statistically significant median ADI score (indicating more disadvantage) compared to those without NEC. No Black infants in the least disadvantaged deciles were diagnosed with NEC.

conclusionBabies from more disadvantaged backgrounds are more likely to develop NEC. This is even more pronounced in Black infants. Further investigation could lead to a more tailored feeding protocol to promote health equity.

Indexed as

extremely low birthweight infantnecrotizing enterocolitisnicuprematuritysocial determinants of health

Identifiers

PMID40726875
PMCPMC12301949

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.