Evidence map›Paper›PMID 40726866›Full record

ArticleCureus2025

Hypoglycemia-Induced Irreversible Brain Injury: A Case Report.

Aakash Bisht, Saliha Erdem, Richa Gupta, Hassan Makki

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aakash BishtInternal Medicine, Detroit Medical Center, Wayne State University, Detroit, USA.
Saliha ErdemInternal Medicine, Detroit Medical Center, Wayne State University, Detroit, USA.
Richa GuptaPediatrics, Government Medical College, Patiala, Patiala, IND.
Hassan MakkiPulmonary, Critical Care and Sleep Medicine, Wayne State University School of Medicine, Detroit, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypoglycemia-induced brain injury, though less common than hyperglycemia, can lead to significant neurological sequelae and mortality. We present a case of a 76-year-old female with a history of poorly controlled diabetes who presented with altered mental status and unresponsiveness. Despite the correction of hypoglycemia and supportive medical management, the patient's neurological status did not improve. Neurological examination revealed myoclonus and severe encephalopathy, prompting further investigation. Imaging studies, including contrast-enhanced CT and MRI of the head, demonstrated findings suggestive of metabolic brain injury, consistent with hypoglycemia-induced encephalopathy. Despite treatment, the patient's condition did not improve, and a decision was made to transition towards comfort-focused care with palliative extubation. This case underscores the challenges in managing hypoglycemia-induced encephalopathy and highlights the importance of timely recognition and intervention in preventing irreversible neurological damage.

Indexed as

anoxic brain injuryhypoglycemia-induced brain injuryirreversible brain injurylow blood glucosepersistent hypoglycemia

Identifiers

PMID40726866
PMCPMC12302933

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.