ArticleJournal of arrhythmia2025
Trajectories of Lipid Profile Changes and Cardiovascular Outcomes in Elderly Asian Patients With Atrial Fibrillation.
Article in Journal of arrhythmia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Trajectories of Lipid Profile Changes and Cardiovascular Outcomes in Elderly Asian Patients With Atrial Fibrillation.Journal of arrhythmia · 2025Article
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Authors and funding
6 authors.
Funding
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Abstract
Background: The relationship between baseline total cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL) and cardiovascular outcomes is well established, but their trajectories over time in elderly Asian patients with atrial fibrillation (AF) remain unexplored. Methods and Results: Using the Taipei Medical University Clinical Research Database from 2013 to 2020, we identified 823 AF patients aged above 75 with at least three annual lipid profile measurements. We used an accelerated failure time (AFT) model to examine the association of trajectories with the primary outcome of composite cardiovascular events (stroke, TIA, myocardial infarction, heart failure hospitalization and cardiovascular death).During follow-up, 308 patients developed events (61.33 per 100 person-years). Three total cholesterol trajectory groups were identified: low (group 1), decreasing (group 2), and middle (group 3). Compared with group 1, individuals in group 3 exhibited a significantly longer event-free survival, with a mean increase of 2.74 years (95% confidence interval [CI]: 1.05-7.12; Conclusion: In this hospital-based cohort study, total cholesterol, LDL, and HDL trajectories are associated with composite cardiovascular outcomes in elderly Asian AF patients.
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