ReviewACS central science2025
Emergent Mechanisms in Biocatalysis.
Review in ACS central science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Machine-Learning-Enabled Rapid Evolution of Photoenzymes for the Asymmetric Synthesis of gem-Difluorophosphonates.Angewandte Chemie (International ed. in English) · 2026Article
- Article
- Establishing the Fatty Acid PhotodecarboxylaseACS catalysis · 2026Article
- Biocatalytic Radical C(spResearch square · 2026Article
- Molecular Origins of Simultaneous Chemo-, Enantio-, and Substrate Selectivity in Non-Natural Photoenzymatic Radical Reactions.Journal of the American Chemical Society · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Enzymes are invaluable tools for solving challenges in synthetic organic chemistry. Beyond replicating native reactivity patterns, modern directed evolution strategies have enabled chemists to efficiently survey chemical space to identify enzyme families capable of catalyzing non-natural reactions. While methods often focus on chemo-, enantio-, and regiocontrol, there are a growing number of examples that describe reactivity patterns and reaction mechanisms that were previously unknown in the synthetic literature. In this Perspective, we will explore examples of such emergent mechanistic pathways of enzymes in the context of synthetic precedents, emphasizing the remarkable versatility of diverse enzyme active sites in controlling unprecedented transformations.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.