ArticleACS central science2025
Decrypting the Nonadiabatic Photoinduced Electron Transfer Mechanism in Light-Sensing Cryptochrome.
Article in ACS central science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Quantum biology: From mechanisms to medicine.Clinical and translational medicine · 2026Review
- Direct Observation of Franck-Condon Stimulated Emission and Sub-20 fs Relaxation in Photoexcited Flavins.The journal of physical chemistry letters · 2026Article
- Molecular Origin of Correlated Bath Effects in Photoinduced Charge Transfer Dynamics in Polar Solvents.The journal of physical chemistry letters · 2026Article
- Protein Electrostatics Tune the Singlet-Triplet Energy Gap in Natural and Engineered Phototropin Light-Oxygen-Voltage (LOV) Domains.Journal of the American Chemical Society · 2026Article
- Consistent and Generalizable Effective Model Hamiltonian Framework for Studying Nonadiabatic Dynamics in the Condensed Phase.Journal of chemical theory and computation · 2025Review
- Following Flavin's Vibrational Modes to Probe Anharmonicities and Low-Lying Conical Intersections.The journal of physical chemistry. B · 2025Article
- Protein and Solvent Reorganization Drives Radical Pair Stability in Avian Cryptochrome 4a.Journal of the American Chemical Society · 2025Article
- Fast-Track Signaling: A Non-Adiabatic Photoactivation Pathway in Plant Cryptochromes.ACS central science · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Cryptochromes are blue light photoreceptors in organisms from plants to animals that are essential for circadian rhythms, phototropism, and magnetoreception. In light-sensing cryptochromes, the photoexcitation of the flavin adenine dinucleotide (FAD) cofactor triggers a cascade of electron transfer (ET) events via a tryptophan chain, eventually generating a radical pair crucial for signaling. Despite extensive studies, the initial photoinduced ET from a neighboring tryptophan residue to FAD remains unclear due to the complexity of simulating all-atom dynamics in excited states, particularly regarding the roles of nonadiabatic pathways and protein environment on the reaction kinetics and quantum efficiency of the ET. To address this gap, we performed extensive nonadiabatic and adiabatic dynamics simulations with on-the-fly multireference
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.