Evidence map›Paper›PMID 40726653›Full record

ArticleJournal of family medicine and primary care2025

The prevalence of vitamin D deficiency and its association to modifiable risk factors of cardiovascular disease among apparently healthy adults in Central Kerala.

Rose Mary Jacob Vatakencherry, Susan John, L Saraswathy, Renjitha Bhaskaran

Abstract read
In one paragraph

Article in Journal of family medicine and primary care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Rose Mary Jacob VatakencherryDepartment of Physiology, Amrita School of Medicine, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.
Susan JohnDepartment of Physiology, Amrita School of Medicine, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.
L SaraswathyDepartment of Physiology, Amrita School of Medicine, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.
Renjitha BhaskaranDepartment of Biostatistics, Amrita School of Medicine, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Cardiovascular diseases remain one of the leading causes of mortality globally with 80% occurring in developing countries. The known modifiable cardiovascular risk factors are Hypertension, Diabetes, Obesity, Hyperlipidaemia, Smoking, and Sedentary lifestyles. The prevalence of these risk factors is highest in Kerala (hypertension 30% and diabetes 14.8%). Globally India has the highest prevalence of cardiovascular disease especially in Kerala. The prevalence of vitamin D deficiency nationally is about 70-100% in some studies but shows contradictory results in various populations in Kerala (children 11% and 89% in perimenopause women). No Known study was done among apparently healthy adults in Kerala. Hence understanding its prevalence and its association if any to the cardiovascular risk factors may help to decrease the prevalence of cardiovascular disease. Methods: Subjects were taken from those who attended the health check-up at a tertiary hospital. Blood parameters like FBS, Triglyceride, High-Density Lipoprotein (HDL), and Serum Vitamin D were analyzed along with Blood pressure and waist circumference. Statistical Analysis: Frequency and Chi-squared test was done to look for prevalence and association of the various cardiovascular risk factors and vitamin D prevalence using IBM SPSS version 20.0 software. Result: It was found that Hypertension was highly prevalent (75%) among the cardiovascular risk factors. The prevalence of deficient and insufficient Vitamin D was 86.9% and it was significantly associated with Hypertension ( Conclusion: High prevalence of deficient and insufficient Vitamin D levels. And this was associated with all the risk factors except obesity. Additional information on low-density lipoprotein, Total Cholesterol, and HbA1c values would be strengthened. Further studies with supplementation preferably done in the community would help to confirm this association.

Indexed as

Diabeteshigh-density lipoproteinhypertensionmodifiable cardiovascular risk factorsobesitytriglyceridesvitamin D

Identifiers

PMID40726653
PMCPMC12296374

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