ArticleAlzheimer's & dementia (Amsterdam, Netherlands)
Loneliness, social isolation, and effects on cognitive decline in patients with dementia: A retrospective cohort study using natural language processing.
Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- How loneliness and social isolation are linked to cognitive decline among older adults? A systematic review of underlying physiological and psychobehavioral mechanisms.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Pooled it
- Article
- Leveraging reddit data for context-enhanced synthetic health data generation to identify low self esteem.Frontiers in psychiatry · 2025Article
- Loneliness, social isolation, and effects on cognitive decline in patients with dementia: A retrospective cohort study using natural language processing.Alzheimer's & dementia (Amsterdam, Netherlands)Article
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Authors and funding
6 authors.
Funding
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Abstract
introductionThe study aimed to compare cognitive trajectories between patients with reports of social isolation and loneliness and those without.
methodsReports of social isolation, loneliness, and Montreal Cognitive Assessment (MoCA) scores were extracted from dementia patients' medical records using natural language processing models and analyed using mixed-effects models.
resultsLonely patients ( DISCUSSION: Lower cognitive levels in lonely and socially isolated patients suggest that these factors may contribute to dementia progression. Highlights: Developed Natural Language Processing model to detect social isolation and loneliness in electronic health records.Patients with loneliness reports have lower Montreal Cognitive Assessment (MoCA) scores than other patients.Social isolation was related to the faster decline in MoCA scores before diagnosis.Social isolation and loneliness are promising targets for slowing cognitive decline.
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