Evidence map›Paper›PMID 40726487›Full record

ArticleFood chemistry: X2025

Formation and stabilization mechanism of heterocyclic aroma compounds / β-CD/CS microcapsules.

Jingyi Hu, Longfei Wang, Meng Zhou, Moyan Dongzhou, Yiran Wang, Menglan Xiao, Mingqin Zhao, Miao Lai

Abstract read
In one paragraph

Article in Food chemistry: X, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jingyi HuFlavors and Fragrance Engineering & Technology Research Center of Henan Province, College of Tobacco Science, Henan Agricultural University, Zhengzhou 450002, China.
Longfei WangFlavors and Fragrance Engineering & Technology Research Center of Henan Province, College of Tobacco Science, Henan Agricultural University, Zhengzhou 450002, China.
Meng ZhouFlavors and Fragrance Engineering & Technology Research Center of Henan Province, College of Tobacco Science, Henan Agricultural University, Zhengzhou 450002, China.
Moyan DongzhouFlavors and Fragrance Engineering & Technology Research Center of Henan Province, College of Tobacco Science, Henan Agricultural University, Zhengzhou 450002, China.
Yiran WangFlavors and Fragrance Engineering & Technology Research Center of Henan Province, College of Tobacco Science, Henan Agricultural University, Zhengzhou 450002, China.
Menglan XiaoFlavors and Fragrance Engineering & Technology Research Center of Henan Province, College of Tobacco Science, Henan Agricultural University, Zhengzhou 450002, China.
Mingqin ZhaoFlavors and Fragrance Engineering & Technology Research Center of Henan Province, College of Tobacco Science, Henan Agricultural University, Zhengzhou 450002, China.
Miao LaiFlavors and Fragrance Engineering & Technology Research Center of Henan Province, College of Tobacco Science, Henan Agricultural University, Zhengzhou 450002, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heterocyclic aroma compounds are a type of edible fragrances with strong nutty and baking aromas, which can improve food flavor. However, their applications are limited due to high volatility and poor stability. Therefore, the development of effective controlled release technologies is required. In this study, five characteristic heterocyclic aroma compounds 2,3-diethyl-5-methylpyrazine (DEMP), 3-ethylpyridine (ELPD), 3-acetylpyridine (ATPD), 5-methylfurfural (MTFF), and furfuryl alcohol (FFAH) were utilized as core materials, and β-cyclodextrin (β-CD)/chitosan (CS) were used as composite wall materials to prepare thermal stabilized microcapsules, with an encapsulation efficiency of 77.43 %-83.32 %. Microcapsules demonstrated superior thermal and storage stability. Furthermore, molecular dynamics (MD) simulations revealed that the primary interactions between the host and guest molecules were van der Waals forces. FFAH/β-CD + CS could form hydrogen bonds more readily. The MM-PBSA result indicated that FFAH/β-CD + CS and ATPD/β-CD + CS microcapsules exhibited greater stability. This research expands the potential applications of heterocyclic aroma compounds in the food industry.

Indexed as

Heterocyclic aroma compoundsMorphological characterizationStabilization mechanismβ-CD/CS microcapsules

Identifiers

PMID40726487
PMCPMC12301814

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.