Evidence map›Paper›PMID 40726477›Full record

ArticleChemistry, an Asian journal2025

Engineering Photolabile Cyclopentane-Fused Coumarins: From One-Pot Synthesis to Mechanistic Study for Visible Light-Triggered Photolysis.

Jau-Tien Lin, Hsuan-Yu Lin, Tai-Chung Lo, Chih-Ling Lin, Yi-Hsien Li, Wei-Hao Wu, Ting-Yi Hsieh, Shun-Yuan Luo, Chih-Chien Chu

Abstract read
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In one paragraph

Article in Chemistry, an Asian journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jau-Tien LinDepartment of Medical Applied Chemistry, Chung Shan Medical University, Taichung, 402, Taiwan.
Hsuan-Yu LinDepartment of Medical Applied Chemistry, Chung Shan Medical University, Taichung, 402, Taiwan.
Tai-Chung LoDepartment of Chemistry, National Chung Hsing University, Taichung, 403, Taiwan.
Chih-Ling LinDepartment of Medical Applied Chemistry, Chung Shan Medical University, Taichung, 402, Taiwan.
Yi-Hsien LiDepartment of Medical Applied Chemistry, Chung Shan Medical University, Taichung, 402, Taiwan.
Wei-Hao WuDepartment of Medical Applied Chemistry, Chung Shan Medical University, Taichung, 402, Taiwan.
Ting-Yi HsiehDepartment of Medical Applied Chemistry, Chung Shan Medical University, Taichung, 402, Taiwan.
Shun-Yuan LuoDepartment of Chemistry, National Chung Hsing University, Taichung, 403, Taiwan.
Chih-Chien ChuDepartment of Medical Applied Chemistry, Chung Shan Medical University, Taichung, 402, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of cyclopentane-fused coumarins were synthesized via a one-pot Heck-Aldol annulation cascade from diethylaminocoumarin derivative and evaluated as visible light-responsive photocages. Compared to conventional coumarin photocages, these fused systems exhibited substantially different photolysis behavior. UV-vis spectroscopic analysis showed distinctive evolution of absorption profiles during photolysis, with pronounced bathochromic shifts and emergence of new bands at 405-415 nm, contrasting sharply with the minimal spectral changes seen in conventional photocages. Kinetic studies revealed that the cyclopentane-fused derivatives underwent significantly slower photorelease (k = 0.2106 h

Indexed as

CoumarinCyclopentane fusionFluorescence tracingPhotocagesPhoto‐elimination

Identifiers

PMID40726477
PMCPMC12498183

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.