Evidence map›Paper›PMID 40726342›Full record

ArticleClinical and translational medicine2025

Bispecific antibody targeting CD40 and HER2 potentiates therapeutic efficacy by reprogramming macrophages within the tumour microenvironment.

Na Li, Ruonan Li, Qiongqiong Ma, Xiaoqi Zhang, Wenxuan Ma, Yi Wang, Baoxin Duan, Kailu Yang, Dongping Zhang, Jiashuo Zhang and 13 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Na LiInstitutes of Biomedical Sciences, School of Life Sciences, Inner Mongolia University, Hohhot, China.
Ruonan LiState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, China.
Qiongqiong MaState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, China.
Xiaoqi ZhangState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, China.
Wenxuan MaState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, China.
Yi WangState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, China.
Baoxin DuanState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, China.
Kailu YangState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, China.
Dongping ZhangState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, China.
Jiashuo ZhangState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, China.
Manping GuState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, China.
Yaxing WuState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, China.
Jiajin SunState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, China.
Huawei WangInstitutes of Biomedical Sciences, School of Life Sciences, Inner Mongolia University, Hohhot, China.
Anqi LiInstitutes of Biomedical Sciences, School of Life Sciences, Inner Mongolia University, Hohhot, China.
Fuquan ChenInstitutes of Biomedical Sciences, School of Life Sciences, Inner Mongolia University, Hohhot, China.
Yiyang BaiState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, China.
Yujie TianState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, China.
Xin LiState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, China.
Yingbin YanDepartment of Oromaxillofacial-Head and Neck Surgery, Tianjin Stomatological Hospital, The Affiliated Stomatological Hospital of Nankai University, Tianjin, China.
Wei WangShanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, China.
Hongkai ZhangState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, China.
Yuan WangInstitutes of Biomedical Sciences, School of Life Sciences, Inner Mongolia University, Hohhot, China.ORCID https://orcid.org/0000-0002-2382-8770

Funding

Inner Mongolia Natural Science Foundation 2024LHMS08043Inner Mongolia Natural Science Foundation 2025MS03090Medical Talent Project of Tianjin City TJSJMYXYC-D2-032National Natural Science Foundation of China 32300670National Natural Science Foundation of China 82261138553National Natural Science Foundation of China 82273843National Natural Science Foundation of China 82373898
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40726342
PMCPMC12304727

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.