Evidence map›Paper›PMID 40726030›Full record

ArticleClinical transplantation2025

Reduced Surgical Complications After Deceased-Donor Kidney Transplantation Using Inverted Allograft and Ultrashort Ureteroureterostomy: A Single-Center Experience.

Rafael Azevedo Foinquinos, Ana Luiza Souza-Leão, Ilan Cubits Kyrillos Oliveira Capela, Thales Paulo Batista, Maria Julia Gonçalves Mello, Cristiano Souza Leão

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Article in Clinical transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Rafael Azevedo FoinquinosDepartment of Urology, Instituto de Medicina Integral Professor Fernando Figueira (IMIP), Recife, Brazil.ORCID https://orcid.org/0000-0001-7687-4386
Ana Luiza Souza-LeãoMedical School, Faculdade Pernambucana de Saúde (FPS), Recife, Brazil.ORCID https://orcid.org/0000-0002-9771-6851
Ilan Cubits Kyrillos Oliveira CapelaMedical School, Faculdade Pernambucana de Saúde (FPS), Recife, Brazil.ORCID https://orcid.org/0000-0002-8962-8923
Thales Paulo BatistaDepartment of Surgery, Universidade Federal de Pernambuco (UFPE), Recife, Brazil.ORCID https://orcid.org/0000-0001-5320-3205
Maria Julia Gonçalves MelloDepartment of Clinical Research, Instituto de Medicina Integral Professor Fernando Figueira (IMIP), Recife, Brazil.ORCID https://orcid.org/0000-0003-4645-8343
Cristiano Souza LeãoDepartment of Surgery, Instituto de Medicina Integral Professor Fernando Figueira (IMIP), Recife, Brazil.ORCID https://orcid.org/0000-0003-2989-117X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe the outcomes of combined inverted renal grafts and ureteroureterostomy as the primary operative approach for kidney transplantation (KTx). PATIENTS AND

methodsThis case series included adult patients who consecutively underwent deceased-donor KTx for end-stage kidney disease at our center between January 2019 and June 2022. All patients received inverted KTx combined with ultrashort anisoperistaltic end-to-side ureteroureterostomy, without ureteral stenting. Descriptive analysis focused on the major perioperative outcomes within 90 days post-transplantation.

resultsCohort analysis of 211 patients revealed major postoperative complications requiring reoperation in 15 patients (7.11%). Reoperations for urological reasons included four patients (1.90%) with ureteral stricture and ureteral fistula in two patients each (0.95%). Ureteral strictures were managed with pyeloureterostomy, and ureteral fistulas were treated with end-to-end ureteral re-anastomosis, double-j stenting, JP drain placement, or pyeloureterostomy. Non-urological complications leading to reoperation included peri-graft collections and infections such as surgical hematoma (1.42%), deep surgical infection (1.90%), and wound dehiscence (1.90%). Three patients (1.42%) ultimately underwent transplantectomy because of graft loss after severe infection in two patients (0.95%) and acute rejection plus infection in one patient (0.47%). All the remaining patients were treated with surgical exploration, evacuation/irrigation, and wound closure. Vascular complications occurred in one patient with an arterial stricture (0.47%). Delayed graft function was found in 82.9% of the patients, with 95.26% achieving resolution within 4 weeks post-transplantation.

conclusionsInverted KTx combined with ultrashort end-to-side ureteroureterostomy is a feasible and safe technique with low rates of urological and vascular complications in our experience. To our knowledge, this is the largest case series using this combined surgical approach as the primary technique for deceased-donor KTxs.

Indexed as

Graft RejectionKidney Failure, ChronicKidney TransplantationPostoperative ComplicationsTissue DonorsUreterUreterostomyAdultAllograftsFemaleFollow-Up StudiesGlomerular Filtration RateGraft SurvivalHumansKidney Function TestsMalemorbidityrenal transplantationsurgical injuriesurethral strictureurinary fistula

Identifiers

PMID40726030
PMCPMC12304622

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.