Evidence map›Paper›PMID 40726014›Full record

ArticleThe journal of obstetrics and gynaecology research2025

Hysterectomy for postpartum hemorrhage in Japan: Diagnostic code validation and nationwide descriptive analysis.

Eishin Nakamura, Tadahiro Goto, Shigetaka Matsunaga, Akihiko Kikuchi, Yasushi Takai, Sayuri Shimizu

Erratum issuedAbstract readValidation Study
In one paragraph

Article in The journal of obstetrics and gynaecology research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Eishin NakamuraCenter for Maternal, Fetal and Neonatal Medicine, Saitama Medical Center, Saitama Medical University, Saitama, Japan.ORCID https://orcid.org/0000-0001-7820-5557
Tadahiro GotoDepartment of Health Data Science, Yokohama City University, Yokohama, Japan.
Shigetaka MatsunagaCenter for Maternal, Fetal and Neonatal Medicine, Saitama Medical Center, Saitama Medical University, Saitama, Japan.ORCID https://orcid.org/0000-0003-2592-9951
Akihiko KikuchiCenter for Maternal, Fetal and Neonatal Medicine, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
Yasushi TakaiDepartment of Obstetrics and Gynecology, Saitama Medical Center, Saitama Medical University, Saitama, Japan.ORCID https://orcid.org/0000-0002-3872-8481
Sayuri ShimizuDepartment of Health Data Science, Yokohama City University, Yokohama, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimHysterectomy is a life-saving procedure for severe postpartum hemorrhage (PPH), but reports on postoperative mortality are limited. This study aimed to describe the rates of hysterectomy and associated mortality in PPH patients using the Diagnosis Procedure Combination (DPC) database, Japan's largest inpatient database.

methodWe first validated the accuracy of PPH diagnostic coding at a tertiary perinatal center, then conducted a nationwide descriptive analysis using DPC data from April 2018 to March 2023. The DPC database includes over half of all acute care hospital admissions in Japan. PPH cases were identified using International Statistical Classification of Diseases and Related Health Problems, 10th Revision codes and blood loss data. We examined hysterectomy rates and postoperative mortality, including a subgroup excluding cases with conditions requiring planned hysterectomy during cesarean section (e.g., placenta previa, accreta, uterine rupture, and cervical cancer).

resultsThe validation study showed high accuracy of PPH coding, with a sensitivity of 97.8% and specificity of 99.7%. Among 209 555 PPH cases, 1835 (0.88%) underwent hysterectomy, with a mortality rate of 0.87% (16 deaths). After excluding 23 039 cases with indications for planned hysterectomy, 681 of 186 516 cases (0.36%) required hysterectomy, with a higher mortality rate of 2.2%.

conclusionsThe DPC database reliably identifies PPH cases. Hysterectomy was performed in 0.88% of all PPH cases, with higher mortality in emergency cases after excluding planned procedures.

Indexed as

Clinical CodingHysterectomyPostpartum HemorrhageAdultDatabases, FactualFemaleHumansJapanPregnancyhealth services researchhysterectomymaternal mortalitynational databasepostpartum hemorrhage

Identifiers

PMID40726014
PMCPMC12582897

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.