Evidence map›Paper›PMID 40726005›Full record

ArticleEuropean journal of oral sciences2025

Evaluation of Streptococcus mutans biofilm formation on fluoride-releasing materials used as pit and fissure sealants.

Patrícia da S L Pereira da Silva, Mariana da Silva Teixeira, Anderson de Araújo Rocha, Rosana Rocha Barros, Lucio Sousa Gonçalves, Mônica Almeida Tostes

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of oral sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Patrícia da S L Pereira da SilvaSchool of Dentistry, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil.ORCID 0000-0003-4306-1658
Mariana da Silva TeixeiraBiomass Study and Water Management Center, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil.ORCID 0009-0005-8082-656X
Anderson de Araújo RochaBiomass Study and Water Management Center, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil.ORCID 0000-0001-5179-1146
Rosana Rocha BarrosDepartment of Microbiology and Parasitology, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil.ORCID 0000-0003-2440-7844
Lucio Sousa GonçalvesSchool of Dentistry, Estácio de Sá University, Rio de Janeiro, Rio de Janeiro, Brazil.ORCID 0000-0002-4388-6310
Mônica Almeida TostesSchool of Dentistry, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil.ORCID 0000-0002-6878-7482

Funding

National Council for Scientific and Technological Development of Brazil (CNPq)
6 · The paper itself

Abstract

This in vitro study evaluated fluoride release and Streptococcus mutans biofilm formation on four types of dental sealants: a giomer, resin-modified glass ionomer, compomer, and a fluoride-free composite (control). Discs were prepared as per the manufacturers' instructions, and they were placed in tubes containing ultrapure water. Fluoride release was measured after 2, 7, and 30 days using ion chromatography, and biofilm formation was analyzed via scanning electron microscopy (SEM). A repeated-measures linear mixed model with log transformation and Bonferroni-corrected post-hoc tests was applied. The resin-modified glass ionomer showed the highest fluoride release, followed by the giomer, with increasing values over time. Compomer and the fluoride-free composite exhibited low, stable fluoride levels. SEM confirmed S. mutans biofilm on all materials. These findings highlight distinct fluoride release profiles and suggest that materials with higher fluoride release may offer improved long-term protection against cariogenic biofilm formation.

Indexed as

BiofilmsCariostatic AgentsFluoridesPit and Fissure SealantsStreptococcus mutansAcrylic ResinsCompomersComposite ResinsGlass Ionomer CementsMaterials TestingMicroscopy, Electron, ScanningSilicon DioxideAcrylic ResinsCariostatic AgentsCompomersComposite ResinsFluoridesglass ionomerGlass Ionomer CementsPit and Fissure SealantsSilicon Dioxidebacterial adhesioncaries dentaldental materialsfluoride treatmentStreptococcus mutans

Identifiers

PMID40726005
PMCPMC12628110

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.