Evidence map›Paper›PMID 40725757›Full record

ReviewJournal of clinical medicine2025

Isolated Tricuspid Regurgitation: When Is Surgery Appropriate? A State-of-the-Art Narrative Review.

Raffaele Barbato, Francesco Loreni, Chiara Ferrisi, Ciro Mastroianni, Riccardo D'Ascoli, Antonio Nenna, Marcello Bergonzini, Mohamad Jawabra, Alessandro Strumia, Massimiliano Carassiti and 3 more

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Raffaele BarbatoUnit of Cardiac Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Rome, Italy.ORCID 0009-0004-8729-655X
Francesco LoreniUnit of Cardiac Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Rome, Italy.ORCID 0000-0002-2577-1843
Chiara FerrisiUnit of Cardiac Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Rome, Italy.ORCID 0009-0008-9375-7403
Ciro MastroianniUnit of Cardiac Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Rome, Italy.ORCID 0000-0002-1263-7143
Riccardo D'AscoliUnit of Cardiac Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Rome, Italy.ORCID 0000-0002-5156-3271
Antonio NennaUnit of Cardiac Surgery, Azienda Ospedaliera Maggiore della Carità, 28100 Novara, Italy.ORCID 0000-0002-4069-6781
Marcello BergonziniUnit of Cardiac Surgery, Hospital Santa Maria Della Misericordia, 06129 Perugia, Italy.
Mohamad JawabraUnit of Cardiac Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Rome, Italy.
Alessandro StrumiaOperative Research Unit of Anesthesia and Intensive Care, Campus Bio-Medico University Hospital, 00128 Rome, Italy.ORCID 0000-0002-3505-1153
Massimiliano CarassitiOperative Research Unit of Anesthesia and Intensive Care, Campus Bio-Medico University Hospital, 00128 Rome, Italy.
Felice AgròOperative Research Unit of Anesthesia and Intensive Care, Campus Bio-Medico University Hospital, 00128 Rome, Italy.
Massimo ChelloUnit of Cardiac Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Rome, Italy.
Mario LusiniUnit of Cardiac Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Rome, Italy.ORCID 0000-0003-0982-0550

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing interest in tricuspid regurgitation (TR) is due to the deep link between mortality and the severity of TR, as well as the limited application of surgical solutions in a setting marked by high in-hospital mortality, attributed to the late presentation of the disease. This delay in intervention is likely associated with a limited understanding of valvular and ventricular anatomy as well as the pathophysiology of the disease, leading to an underestimation of TR severity. With the rapid development of transcatheter solutions showing early safety and efficacy, there is a growing necessity to accurately understand and diagnose the valvular disease process to determine suitable management strategies. This review will outline the normal and pathological anatomy of the tricuspid valve, classify the anatomical substrates of TR, and present new risk stratification methods to determine the appropriate timing for both medical and surgical treatment.

Indexed as

gradingregurgitationscoretranscathetertricuspid valvevalve repairvalve replacementvalve surgery

Identifiers

PMID40725757
PMCPMC12295814

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.