Evidence map›Paper›PMID 40725701›Full record

ReviewJournal of clinical medicine2025

Tricuspid Regurgitation in the Era of Transcatheter Interventions: The Pivotal Role of Multimodality Imaging.

Valeria Maria De Luca, Stefano Censi, Rita Conti, Roberto Nerla, Sara Bombace, Tobias Friedrich Ruf, Ralph Stephan von Bardeleben, Philipp Lurz, Fausto Castriota, Angelo Squeri

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Valeria Maria De LucaGVM Care & Research, Maria Cecilia Hospital, 48033 Cotignola, Italy.ORCID 0009-0005-3276-3373
Stefano CensiGVM Care & Research, Maria Cecilia Hospital, 48033 Cotignola, Italy.ORCID 0000-0002-9893-3508
Rita ContiGVM Care & Research, Maria Cecilia Hospital, 48033 Cotignola, Italy.
Roberto NerlaGVM Care & Research, Maria Cecilia Hospital, 48033 Cotignola, Italy.
Sara BombaceDepartment of Cardiology, University Medical Center Mainz, 55131 Mainz, Germany.
Tobias Friedrich RufDepartment of Cardiology, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0000-0003-4540-6621
Ralph Stephan von BardelebenDepartment of Cardiology, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0000-0002-1356-0037
Philipp LurzDepartment of Cardiology, University Medical Center Mainz, 55131 Mainz, Germany.
Fausto CastriotaGVM Care & Research, Maria Cecilia Hospital, 48033 Cotignola, Italy.
Angelo SqueriGVM Care & Research, Maria Cecilia Hospital, 48033 Cotignola, Italy.ORCID 0000-0001-9115-5443

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the last ten years, transcatheter tricuspid valve interventions (TTVIs) have emerged as effective options for symptomatic patients with moderate-to-severe tricuspid regurgitation (TR) who are at prohibitive surgical risk. Successful application of these therapies depends on a patient-tailored, multimodal imaging workflow. Transthoracic and transesophageal echocardiography remain the first-line diagnostic tools, rapidly stratifying TR severity, mechanism, and right ventricular function, and identifying cases requiring further evaluation. Cardiac computed tomography (CT) then provides anatomical detail-quantifying tricuspid annular dimension, leaflet tethering, coronary artery course, and venous access anatomy-to refine candidacy and simulate optimal device sizing and implantation angles. In patients with suboptimal echocardiographic windows or equivocal functional data, cardiovascular magnetic resonance (CMR) offers gold-standard quantification of RV volumes, ejection fraction, regurgitant volume, and tissue characterization to detect fibrosis. Integration of echo-derived parameters, CT anatomical notes, and CMR functional assessment enables the heart team to better select patients, plan procedures, and determine the optimal timing, thereby maximizing procedural success and minimizing complications. This review describes the current strengths, limitations, and future directions of multimodality imaging in comprehensive evaluations of TTVI candidates.

Indexed as

multimodality imagingtranscatheter tricuspid valve interventionstricuspid regurgitationtricuspid valve disease

Identifiers

PMID40725701
PMCPMC12295391

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.