Evidence map›Paper›PMID 40725670›Full record

ReviewJournal of clinical medicine2025

Sailing Across Contraception, Pregnancy, and Breastfeeding: The Complex Journey of Women with Cardiomyopathies.

Maria Cristina Carella, Vincenzo Ezio Santobuono, Francesca Maria Grosso, Marco Maria Dicorato, Paolo Basile, Ilaria Dentamaro, Maria Ludovica Naccarati, Daniela Santoro, Francesco Monitillo, Rosanna Valecce and 11 more

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Maria Cristina CarellaCardiology Unit, Department of Interdisciplinary Medicine (DIM), University of Bari "Aldo Moro", University Hospital Consortium Polyclinic of Bari, 70124 Bari, Italy.ORCID 0000-0002-5094-2237
Vincenzo Ezio SantobuonoCardiology Unit, Department of Interdisciplinary Medicine (DIM), University of Bari "Aldo Moro", University Hospital Consortium Polyclinic of Bari, 70124 Bari, Italy.ORCID 0000-0002-8746-729X
Francesca Maria GrossoInternal Medicine Section, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", University Hospital Consortium Polyclinic of Bari, 70124 Bari, Italy.
Marco Maria DicoratoCardiology Unit, Department of Interdisciplinary Medicine (DIM), University of Bari "Aldo Moro", University Hospital Consortium Polyclinic of Bari, 70124 Bari, Italy.ORCID 0009-0008-4865-2522
Paolo BasileCardiology Unit, Department of Interdisciplinary Medicine (DIM), University of Bari "Aldo Moro", University Hospital Consortium Polyclinic of Bari, 70124 Bari, Italy.ORCID 0000-0002-2327-7585
Ilaria DentamaroCardiology Unit, Department of Interdisciplinary Medicine (DIM), University of Bari "Aldo Moro", University Hospital Consortium Polyclinic of Bari, 70124 Bari, Italy.
Maria Ludovica NaccaratiCardiology Unit, Department of Interdisciplinary Medicine (DIM), University of Bari "Aldo Moro", University Hospital Consortium Polyclinic of Bari, 70124 Bari, Italy.
Daniela SantoroCardiology Unit, Department of Interdisciplinary Medicine (DIM), University of Bari "Aldo Moro", University Hospital Consortium Polyclinic of Bari, 70124 Bari, Italy.ORCID 0000-0002-0506-560X
Francesco MonitilloCardiology Unit, Department of Interdisciplinary Medicine (DIM), University of Bari "Aldo Moro", University Hospital Consortium Polyclinic of Bari, 70124 Bari, Italy.ORCID 0000-0002-8327-1468
Rosanna ValecceUOC Cardiologia, Ospedale Di Venere, Asl Bari, 70124 Bari, Italy.
Roberta RuggieriUOC Cardiologia, Ospedale Di Venere, Asl Bari, 70124 Bari, Italy.
Aldo AgeaCardiology Unit, Department of Interdisciplinary Medicine (DIM), University of Bari "Aldo Moro", University Hospital Consortium Polyclinic of Bari, 70124 Bari, Italy.
Martino PepeCardiology Unit, Department of Interdisciplinary Medicine (DIM), University of Bari "Aldo Moro", University Hospital Consortium Polyclinic of Bari, 70124 Bari, Italy.
Gianluca PontoneDepartment of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, 20133 Milan, Italy.
Antonella VimercatiUnit of Obstetrics and Gynecology, Department of Interdisciplinary Medicine (DIM), University of Bari "Aldo Moro", University Hospital Consortium Polyclinic of Bari, 70124 Bari, Italy.ORCID 0000-0002-9862-1619
Ettore CicinelliUnit of Obstetrics and Gynecology, Department of Interdisciplinary Medicine (DIM), University of Bari "Aldo Moro", University Hospital Consortium Polyclinic of Bari, 70124 Bari, Italy.ORCID 0000-0003-2390-4582
Nicola LaforgiaNeonatology and Neonatal Intensive Care Unit, Department of Interdisciplinary Medicine (DIM), University of Bari "Aldo Moro", University Hospital Consortium Polyclinic of Bari, 70124 Bari, Italy.ORCID 0000-0002-4610-1216
Nicoletta RestaMedical Genetics Unit, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", University Hospital Consortium Polyclinic of Bari, 70124 Bari, Italy.ORCID 0000-0001-8640-5532
Andrea Igoren GuaricciCardiology Unit, Department of Interdisciplinary Medicine (DIM), University of Bari "Aldo Moro", University Hospital Consortium Polyclinic of Bari, 70124 Bari, Italy.ORCID 0000-0001-7133-4401
Marco Matteo CicconeCardiology Unit, Department of Interdisciplinary Medicine (DIM), University of Bari "Aldo Moro", University Hospital Consortium Polyclinic of Bari, 70124 Bari, Italy.
Cinzia ForleoCardiology Unit, Department of Interdisciplinary Medicine (DIM), University of Bari "Aldo Moro", University Hospital Consortium Polyclinic of Bari, 70124 Bari, Italy.ORCID 0000-0002-9452-4037

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gender-specific cardiology has gained increasing recognition in recent years, emphasizing the need for tailored management strategies for women with cardiovascular disease. Among these, cardiomyopathies-dilated, arrhythmogenic, hypertrophic, and restrictive-pose unique challenges throughout a woman's reproductive life, affecting contraception choices, pregnancy outcomes, and breastfeeding feasibility. Despite significant advances in cardiovascular care, there is still limited guidance on balancing maternal safety and neonatal well-being in this complex setting. This review provides a comprehensive overview of the current evidence on reproductive counseling, pregnancy management, and postpartum considerations in women with cardiomyopathies. We discuss the cardiovascular risks associated with each cardiomyopathy subtype during pregnancy, highlighting risk stratification tools and emerging therapeutic strategies. Additionally, we address the safety and implications of breastfeeding, an often overlooked but increasingly relevant aspect of postpartum care. A multidisciplinary approach involving cardiologists, gynecologists, obstetricians, and anesthesiologists is crucial to optimizing maternal and fetal outcomes. Improved risk assessment, tailored patient counseling, and careful management strategies are essential to ensuring safer reproductive choices for women with cardiomyopathy. From now on, greater attention is expected to be given to bridging existing knowledge gaps, promoting a more personalized and evidence-based approach to managing these patients throughout different stages of reproductive life.

Indexed as

breastfeedingcardiomyopathygender differencesgynecologylactationneonatologyobstetricspregnancyreproductive healthsexual healthwomen’s health

Identifiers

PMID40725670
PMCPMC12295082

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.