Evidence map›Paper›PMID 40725528›Full record

ReviewJournal of clinical medicine2025

Endoscopic Ultrasound as a Diagnostic Tool for the Mediastinum and Thorax.

Sara Nikolic, Lucía Guilabert, Giuseppe Vanella, Catalina Vladut, Giuseppe La Mattina, Giuseppe Infantino, Elio D'Amore, Cecilie Siggaard Knoph, Giacomo Emanuele Maria Rizzo

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sara NikolicDepartment of Gastroenterology, University Medical Center Maribor, 2000 Maribor, Slovenia.ORCID 0000-0003-3751-2619
Lucía GuilabertGastroenterology Department, Dr. Balmis General University Hospital, Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL), 03010 Alicante, Spain.ORCID 0000-0002-9597-6377
Giuseppe VanellaDivision of Pancreato-Biliary Endoscopy and Endosonography, Pancreas Translational and Clinical Research Center, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, 20132 Milan, Italy.ORCID 0000-0001-7280-1761
Catalina VladutDepartment of Gastroenterology, "Prof. Dr. Agrippa Ionescu" Clinical Emergency Hospital, 011356 Bucharest, Romania.
Giuseppe La MattinaBroncopneumologia Interventistica, AOOR Villa Sofia Cervello, 90127 Palermo, Italy.
Giuseppe InfantinoGastroenterology and Endoscopy Unit, Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione, IRCCS-ISMETT, 90127 Palermo, Italy.
Elio D'AmoreGastroenterology and Endoscopy Unit, Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione, IRCCS-ISMETT, 90127 Palermo, Italy.
Cecilie Siggaard KnophCentre for Pancreatic Diseases, Department of Gastroenterology & Hepatology, Aalborg University Hospital, 9100 Aalborg, Denmark.ORCID 0000-0002-8373-1487
Giacomo Emanuele Maria RizzoGastroenterology and Endoscopy Unit, Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione, IRCCS-ISMETT, 90127 Palermo, Italy.ORCID 0000-0001-9335-6740

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endoscopic ultrasound (EUS) is a helpful tool for the study of the mediastinum, a challenging region for both transesophageal and endobronchial (EBUS) endosonography. This area is divided into sections and contains numerous lymph nodes essential for the staging and diagnosis of conditions like lung cancer, sarcoidosis, and infections. EUS allows for detailed examination of the mediastinal region, identifying various kinds of abnormalities, whether they are benign cysts or malignant tumors. The aim of this narrative review is to provide a clear overview of how EUS contributes to mediastinal diagnostics and to offer practical insights for clinicians. A comprehensive, non-systematic search of PubMed was conducted by the authors to identify relevant studies. EUS methods, such as elastography and contrast-enhanced imaging, have improved diagnosis by analyzing tissue stiffness and blood flow, and they help endosonographers distinguish between different conditions. EUS-guided tissue sampling techniques, like fine needle aspiration and biopsy, are crucial for detecting cancer and examining lymph nodes in a minimally invasive way. By combining EUS with endobronchial ultrasound, operators can achieve more accurate results, especially in cancer staging and treatment planning. Overall, this approach is a key tool in treating thoracic and mediastinal conditions.

Indexed as

bronchoscopyEBUSendoscopyEUSlung massesmediastinum

Identifiers

PMID40725528
PMCPMC12294957

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.