Evidence map›Paper›PMID 40725489›Full record

ArticleGenes2025

Patchy Phylogenetic Distribution and Poor Translational Adaptation of a Nested ORF in the Mammalian Mitochondrial

Sheng-Lin Shi, Dan-Tong Li, Yan-Qun Liu

Abstract read
In one paragraph

Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sheng-Lin ShiCollege of Bioscience and Biotechnology, Shenyang Agricultural University, Shenyang 110866, China.ORCID 0000-0002-1176-4327
Dan-Tong LiCollege of Bioscience and Biotechnology, Shenyang Agricultural University, Shenyang 110866, China.
Yan-Qun LiuCollege of Bioscience and Biotechnology, Shenyang Agricultural University, Shenyang 110866, China.ORCID 0000-0001-9025-1986

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe mammalian mitochondrial genome has long been considered to encode only 13 proteins. However, a recent study identified a nested alternative open reading frame (nAltORF) within the primate mitochondrial

methodsThis study conducted a comprehensive bioinformatic analysis of nested

resultsNested

conclusionsThese findings collectively suggest that while

Indexed as

Cytochromes bMitochondriaOpen Reading FramesProtein BiosynthesisAnimalsEvolution, MolecularGenome, MitochondrialHumansMammalsPhylogenyPrimatesRodentiaCytochromes bcodon adaptation indexcodon usage similaritycytb genedispensable geneKozak sequencemitochondrial proteinnested ORF

Identifiers

PMID40725489
PMCPMC12294625

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.