Evidence map›Paper›PMID 40725483›Full record

ArticleGenes2025

Boosting Genomic Prediction Transferability with Sparse Testing.

Osval A Montesinos-López, Jose Crossa, Paolo Vitale, Guillermo Gerard, Leonardo Crespo-Herrera, Susanne Dreisigacker, Carolina Saint Pierre, Iván Delgado-Enciso, Abelardo Montesinos-López, Reka Howard

Abstract read
In one paragraph

Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Osval A Montesinos-LópezFacultad de Telemática, Universidad de Colima, Colima 28040, Col., Mexico.
Jose CrossaInternational Maize and Wheat Improvement Center (CIMMYT), Km 45, Carretera Mexico-Veracruz, Texcoco 52640, Edo. Mex., Mexico.
Paolo VitaleInternational Maize and Wheat Improvement Center (CIMMYT), Km 45, Carretera Mexico-Veracruz, Texcoco 52640, Edo. Mex., Mexico.
Guillermo GerardInternational Maize and Wheat Improvement Center (CIMMYT), Km 45, Carretera Mexico-Veracruz, Texcoco 52640, Edo. Mex., Mexico.
Leonardo Crespo-HerreraInternational Maize and Wheat Improvement Center (CIMMYT), Km 45, Carretera Mexico-Veracruz, Texcoco 52640, Edo. Mex., Mexico.ORCID 0000-0003-0506-4700
Susanne DreisigackerInternational Maize and Wheat Improvement Center (CIMMYT), Km 45, Carretera Mexico-Veracruz, Texcoco 52640, Edo. Mex., Mexico.ORCID 0000-0002-3546-5989
Carolina Saint PierreInternational Maize and Wheat Improvement Center (CIMMYT), Km 45, Carretera Mexico-Veracruz, Texcoco 52640, Edo. Mex., Mexico.ORCID 0000-0003-1291-7468
Iván Delgado-EncisoSchool of Medicine, University of Colima, Colima 28040, Col., Mexico.ORCID 0000-0001-9848-862X
Abelardo Montesinos-LópezCentro Universitario de Ciencias Eactas e Ingenierías (CUCEI), Universidad de Guadalajara, Guadalajara 44430, Jal., Mexico.
Reka HowardDepartment of Statistics, University of Nebraska-Lincoln, 343C Hardin Hall, Lincoln, NE 68583-0963, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesImproving sparse testing is essential for enhancing the efficiency of genomic prediction (GP). Accordingly, new strategies are being explored to refine genomic selection (GS) methods under sparse testing conditions.

methodsIn this study, a sparse testing approach was evaluated, specifically in the context of predicting performance for tested lines in untested environments. Sparse testing is particularly practical in large-scale breeding programs because it reduces the cost and logistical burden of evaluating every genotype in every environment, while still enabling accurate prediction through strategic data use. To achieve this, we used training data from CIMMYT (Obregon, Mexico), along with partial data from India, to predict line performance in India using observations from Mexico.

resultsOur results show that incorporating data from Obregon into the training set improved prediction accuracy, with greater effectiveness when the data were temporally closer. Across environments, Pearson's correlation improved by at least 219% (in a testing proportion of 50%), while gains in the percentage of matching in top 10% and 20% of top lines were 18.42% and 20.79%, respectively (also in a testing proportion of 50%).

conclusionsThese findings emphasize that enriching training data with relevant, temporally proximate information is key to enhancing genomic prediction performance; conversely, incorporating unrelated data can reduce prediction accuracy.

Indexed as

GenomicsPlant BreedingGenotypeIndiaMexicoModels, GeneticSelection, Geneticgenomic predictionsparse testingtested lines in untested environment

Identifiers

PMID40725483
PMCPMC12294251

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.