Evidence map›Paper›PMID 40725480›Full record

ArticleGenes2025

A Subset of HOX Genes Negatively Correlates with HOX/PBX Inhibitor Target Gene Expression and Is Associated with Apoptosis, DNA Repair, and Metabolism in Prostate Cancer.

Richard Morgan, Christopher Smith, Hardev Pandha

Abstract read
In one paragraph

Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Richard MorganSchool of Medicine and Biosciences, University of West London, St Mary's Road, London W5 5RF, UK.ORCID 0000-0002-8721-4479
Christopher SmithFaculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, UK.ORCID 0000-0001-9116-9482
Hardev PandhaFaculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesThe

methodsWe analyzed publicly available transcriptomic data in the R2 platform.

resultsWe show that a specific subgroup of

conclusionsOur findings indicate these HOX genes may have pro-oncogenic functions in prostate cancer.

Indexed as

ApoptosisDNA RepairGenes, HomeoboxHomeodomain ProteinsPre-B-Cell Leukemia Transcription Factor 1Prostatic NeoplasmsGene Expression Regulation, NeoplasticHumansMaleHomeodomain ProteinsPre-B-Cell Leukemia Transcription Factor 1ageingATF3DUSP1HOXHXR9PBX

Identifiers

PMID40725480
PMCPMC12294241

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.