Evidence map›Paper›PMID 40725453›Full record

ArticleGenes2025

Genetic Factors Associated with Intraocular Inflammation After Brolucizumab Administration in Patients with Exudative Age-Related Macular Degeneration.

Seigo Yoneyama, Yoichi Sakurada, Taiyo Shijo, Yoshiko Fukuda, Yumi Kotoda, Wataru Kikushima, Fumihiko Mabuchi, Kenji Kashiwagi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Observational
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Seigo YoneyamaDepartment of Ophthalmology, Faculty of Medicine, University of Yamanashi, Yamanashi 409-3898, Japan.
Yoichi SakuradaDepartment of Ophthalmology, Faculty of Medicine, University of Yamanashi, Yamanashi 409-3898, Japan.ORCID 0000-0002-2894-0454
Taiyo ShijoDepartment of Ophthalmology, Faculty of Medicine, University of Yamanashi, Yamanashi 409-3898, Japan.
Yoshiko FukudaDepartment of Ophthalmology, Faculty of Medicine, University of Yamanashi, Yamanashi 409-3898, Japan.
Yumi KotodaDepartment of Ophthalmology, Faculty of Medicine, University of Yamanashi, Yamanashi 409-3898, Japan.
Wataru KikushimaDepartment of Ophthalmology, Faculty of Medicine, University of Yamanashi, Yamanashi 409-3898, Japan.
Fumihiko MabuchiDepartment of Ophthalmology, Faculty of Medicine, University of Yamanashi, Yamanashi 409-3898, Japan.
Kenji KashiwagiDepartment of Ophthalmology, Faculty of Medicine, University of Yamanashi, Yamanashi 409-3898, Japan.ORCID 0000-0001-8506-8503

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antibodies, Monoclonal, HumanizedInflammationMacular DegenerationWet Macular DegenerationAgedAged, 80 and overCholesterol Ester Transfer ProteinsComplement Factor HFemaleGenetic Predisposition to DiseaseGenotypeHumansIntravitreal InjectionsMalePolymorphism, Single NucleotideAntibodies, Monoclonal, HumanizedbrolucizumabCETP protein, humanCholesterol Ester Transfer ProteinsComplement Factor Hage-related macular degenerationbrolucizumabCETPintraocular inflammation

Identifiers

PMID40725453
PMCPMC12294146

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.